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| | TRIFLUOROACETALDEHYDE HYDRATE Basic information |
| Product Name: | TRIFLUOROACETALDEHYDE HYDRATE | | Synonyms: | Trifluoroacetaldehyde hydrate (diol), Tech.;Trifluoroethanal hydrate;TRIFLUOROACETALDEHYDE HYDRAT;Trifluoracetaldehyde monohydrate,~75% in water;Trifluoroacetaldehyde hydrate, technical, 75%;Trifluoroacetaldehyde monohydrate, 75% aqueous solution;2,2,2-Trifluoro-1,1-ethanediol (contains Total ca. 25% Water);2,2,2-Trifluoro-1,1-ethanediol (contains Total ca. 35% Water) | | CAS: | 421-53-4 | | MF: | C2H3F3O2 | | MW: | 116.04 | | EINECS: | 207-006-4 | | Product Categories: | OLED | | Mol File: | 421-53-4.mol |  |
| | TRIFLUOROACETALDEHYDE HYDRATE Chemical Properties |
| Melting point | 69-70℃ | | Boiling point | 104-106°C | | density | 1,4 g/cm3 | | refractive index | 1.33 | | RTECS | KI2850000 | | Fp | 104-106°C | | storage temp. | Storage temp. 2-8°C | | pka | 10.22±0.41(Predicted) | | form | clear liquid | | color | Colorless to Almost colorless | | Water Solubility | Soluble in water. | | InChI | InChI=1S/C2H3F3O2/c3-2(4,5)1(6)7/h1,6-7H | | InChIKey | VGJWVEYTYIBXIA-UHFFFAOYSA-N | | SMILES | C(O)(O)C(F)(F)F | | CAS DataBase Reference | 421-53-4(CAS DataBase Reference) | | EPA Substance Registry System | 1,1-Ethanediol, 2,2,2-trifluoro- (421-53-4) |
| Hazard Codes | T | | Risk Statements | 20/21/22-43-36-22-11 | | Safety Statements | 24/25-36/37-26-16 | | RIDADR | 1989 | | Hazard Note | Toxic | | TSCA | TSCA listed | | HazardClass | 3 | | PackingGroup | III | | HS Code | 29130000 | | Toxicity | LD50 oral in mouse: 600mg/kg |
| | TRIFLUOROACETALDEHYDE HYDRATE Usage And Synthesis |
| Chemical Properties | colourless liquid | | Uses | Trifluoroacetaldehyde monohydrate is used as an agricultural
chemical, a drug and therapeutic agent, a fungicide, bactericide,
and wood preservative. | | Uses | One general application of trifluoroacetaldehyde is the preparation of trifluoroethylamino derivatives via reductive amination reaction. This synthesis includes the formation of the corresponding N,O-acetal intermediates followed by their reduction using NaBH4or 2-picoline borane complex, affording the target trifluoroethylamino compounds in moderate to good yields. Another general application of trifluoroacetaldehyde is the synthesis of chiral α-substituted trifluoroethylamino compounds. | | Safety Profile | Moderately toxic by ingestion,intravenous, and intraperitoneal routes. When heated todecomposition it emits very toxic fumes of F. | | Synthesis | Raw materials with components of 1,1,1-trifluoroethane, oxygen, and nitrogen were mixed and preheated at a molar ratio of 1:1.5:1~10 and then injected into a fixed-bed reactor, and reacted with 2%~16% Fe2O3/AlF3 or 2%~16% CuO/AlF3 as a catalyst at 0.1~2 MPa and 200~400C. The reaction was carried out continuously, and the exported product was absorbed with water and trifluoroacetaldehyde hydrate was isolated. |
| | TRIFLUOROACETALDEHYDE HYDRATE Preparation Products And Raw materials |
| Raw materials | Ethanol, 2,2,2-trifluoro-1-(2,2,2-trifluoroethoxy)--->TRIFLUOROACETALDEHYDE-->1,1,1-trifluoro-3-nitropropane-->Phenyl (trifluoromethyl) sulfone-->Trifluoroacetonitrile-->1,1,1-TRIFLUOROPROPANE-->Acetaldehyde-->TRIFLUOROACETALDEHYDE ETHYL HEMIACETAL-->2,2,2-Trifluoroethanol-->Trifluoroacetic acid-->Trifluoromethane-->Formaldehyde-->Trifluoroacetic anhydride |
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