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| | N-HydroxysucciniMidyl Pyrenebutanoate Basic information |
| Product Name: | N-HydroxysucciniMidyl Pyrenebutanoate | | Synonyms: | Pyrenebutanonate-NHS ester;1-succinimidyl-3’-pyrenebutyrate;1-PYRENEBUTYRIC ACID N-HYDROXYSUCCINIMI&;Pyrenebutyric acid NHS ester;1-[1-Oxo-4-(pyrenyl)butoxy]-
2,5-pyrrolidinedione;1-Pyrenebutanoic Acid 2,5-Dioxo-1-pyrrolidinyl Ester;4-(1-Pyrene)butanoic Acid SucciMidyl Ester;4-(1-Pyrene)butyric Acid N-HydroxysucciniMide Ester | | CAS: | 114932-60-4 | | MF: | C24H19NO4 | | MW: | 385.41 | | EINECS: | | | Product Categories: | P;Stains and Dyes;Stains&Dyes, A to | | Mol File: | 114932-60-4.mol |  |
| | N-HydroxysucciniMidyl Pyrenebutanoate Chemical Properties |
| Melting point | 132-136 °C(lit.) | | storage temp. | room temp | | solubility | Soluble in chloroform, N,N-
dimethylformamide, dimethyl sulfoxide, methanol | | form | A solid | | color | Yellow solid | | Appearance | off-white solid | | λmax | 340nm, 325nm (MeOH) | | Biological Applications | Characterizing
cyclodextrin-based polyrotaxanes; detecting
nucleic acids,polyamines;immobilizing
proteins;probing lysozyme in human serum;
as a substrate for measuring polymerases activity,
recombinases activity, topoisomerases activity | | Major Application | Carbon nanotubes
(single-wall carbon nanotubes (SWCNT) and multi-wall
carbon nanotubes (MWCNTs)); cellulose
materials for bulky paper sheets; graphene-based
polymer nanocomposites materials/films;
photonic materials;photovoltaic devices;
polyaniline systems;poly(dimethylsiloxane) (PDMS)
oligomers;poly(propylene imine) dendrimers;
thin-films | | InChI | InChI=1S/C24H19NO4/c26-20-13-14-21(27)25(20)29-22(28)6-2-3-15-7-8-18-10-9-16-4-1-5-17-11-12-19(15)24(18)23(16)17/h1,4-5,7-12H,2-3,6,13-14H2 | | InChIKey | YBNMDCCMCLUHBL-UHFFFAOYSA-N | | SMILES | C1(CCCC(ON2C(=O)CCC2=O)=O)=C2C3=C4C(C=C2)=CC=CC4=CC=C3C=C1 |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | HS Code | 2928.00.5000 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | N-HydroxysucciniMidyl Pyrenebutanoate Usage And Synthesis |
| Description | Pyrene is a polyaromatic hydrocarbon which exhibits fluorescence in blue range of the spectrum. When two pyrene residues are closely spaced, excimer fluorescence is observed at longer wavelength. Therefore, pyrene is useful as a proximity label.
Pyrene exhibits affinity to graphite, and can be used as an anchor group for graphite. This reagent can be conjugated with biomolecules for their subsequent immobilization on graphite surfaces.
This NHS ester allows to label biomolecules with amino groups, such as proteins, peptides, amino-DNA and other molecules.
Pyrene is also a FRET donor for perylene. | | Uses | N-Hydroxysuccinimidyl Pyrenebutanoate is a novel fluorescent monomer used as new material for protein conjugation. Dyes and metabolites. | | General Description | 1-Pyrenebutyric acid N-hydroxysuccinimide ester (PANHS) is an aromatic chemical, which is also known as PBSE. It is a yellow solid, that is soluble in chloroform, N,N dimethyl formamide, dimethyl sulfoxide and methanol. It is used in detecting nucleic acids, characterizing cyclodextrin based polyrotaxanes, immobilizing proteins etc. | | Abs/Em Maxima | 343; 326; 313; 276; 265; 242; 234/377; 397 nm |
| | N-HydroxysucciniMidyl Pyrenebutanoate Preparation Products And Raw materials |
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