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| | diethyl 2-(((9H-fluoren-9-yl)methoxy)carbonyloxyimino)-2-c Basic information |
| Product Name: | diethyl 2-(((9H-fluoren-9-yl)methoxy)carbonyloxyimino)-2-c | | Synonyms: | diethyl 2-(((9H-fluoren-9-yl)methoxy)carbonyloxyimino)-2-c;(E)-(ethyl cyano[({[(9H-fluoren-9-yl)methoxy]carbonyl}oxy)imino]formate);Acetic acid, 2-cyano-2-[[[(9H-fluoren-9-ylmethoxy)carbonyl]oxy]imino]-, ethyl ester;Fmoc-Emox;diethyl 2-{[(9H-fluoren-9-yl)methoxy]carbonyloxyimino}-2-cyanoacetate;Ethyl 2-(((((9H-fluoren-9-yl)methoxy)carbonyl)oxy)imino)-2-cyanoacetate;Ethyl 2-cyano-2-[(Fmoc-oxy)imino]acetate | | CAS: | 1235983-26-2 | | MF: | C20H16N2O5 | | MW: | 364.35 | | EINECS: | | | Product Categories: | | | Mol File: | 1235983-26-2.mol |  |
| | diethyl 2-(((9H-fluoren-9-yl)methoxy)carbonyloxyimino)-2-c Chemical Properties |
| Melting point | 174-175 °C(Solv: dichloromethane (75-09-2); benzene (71-43-2)) | | Boiling point | 501.6±43.0 °C(Predicted) | | density | 1.28±0.1 g/cm3(Predicted) | | storage temp. | Store at +2°C to +8°C. | | form | powder | | Major Application | peptide synthesis | | InChI | InChI=1S/C20H16N2O5/c1-2-25-19(23)18(11-21)22-27-20(24)26-12-17-15-9-5-3-7-13(15)14-8-4-6-10-16(14)17/h3-10,17H,2,12H2,1H3 | | InChIKey | VCVOYTUCBKLQSK-UHFFFAOYSA-N | | SMILES | C(OCC)(=O)C(C#N)=NOC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | diethyl 2-(((9H-fluoren-9-yl)methoxy)carbonyloxyimino)-2-c Usage And Synthesis |
| Uses | A novel derivative for introduction of Fmoc protecting group to hindered amino acids with negligible formation of β-alanyl related impurities [1].
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Literature references
[1] S. N. Khattab, et al. (2010) Eur. J. Org. Chem., 3275. |
| | diethyl 2-(((9H-fluoren-9-yl)methoxy)carbonyloxyimino)-2-c Preparation Products And Raw materials |
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