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| | Endophilin-1 (E1E6Q) Rabbit mAb Chemical Properties |
| | Endophilin-1 (E1E6Q) Rabbit mAb Usage And Synthesis |
| Source | Rabbit | | Reactivity | Human;Mouse | | Background | Endophilin proteins are part of a large family of Bin/Amphiphysin/Rvs domain proteins that are involved in cell membrane remodeling. The endophilins are encoded by five genes, which produce endophilin A 1-3 and B 1-2. Endophilins are involved in many cellular mechanisms, such as synaptic vesicle recycling, receptor trafficking, and membrane remodeling processes. Research studies indicate that endophilin 1 can induce different membrane shapes and participate in the morphogenesis of dendritic spines. Endophilin 1 is also involved in regulating blood brain barrier permeability via the EGFR-JNK pathway. | | References | [1] Safari, F. and Suetsugu, S. (2012) Membranes (Basel) 2, 91-117.
[2] Kjaerulff, O. et al. (2011) Cell Biochem Biophys 60, 137-54.
[3] Ambroso, M.R. et al. (2014) Proc Natl Acad Sci U S A 111, 6982-7.
[4] Yang, Y. et al. (2015) Cell Res 25, 496-516.
[5] Chen, L. et al. (2015) Brain Res 1606, 44-53. |
| | Endophilin-1 (E1E6Q) Rabbit mAb Preparation Products And Raw materials |
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