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| | Domperidone Impurity 15 Basic information |
| Product Name: | Domperidone Impurity 15 | | Synonyms: | Domperidone Impurity 15;2H-Benzimidazol-2-one, 1,3-bis(3-chloropropyl)-1,3-dihydro-;1,3-Bis(3-chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one;1,3-Bis(3-Chloropropyl)-1,3-dihydro-2H-benzo[d]imidazol-2-one | | CAS: | 142799-22-2 | | MF: | C13H16Cl2N2O | | MW: | 287.18 | | EINECS: | | | Product Categories: | | | Mol File: | 142799-22-2.mol |  |
| | Domperidone Impurity 15 Chemical Properties |
| Melting point | 66°C | | storage temp. | -20°C Freezer | | solubility | Chloroform (Slightly), Water (Slightly, Heated, Sonicated) | | form | Solid | | color | White to Off-White |
| | Domperidone Impurity 15 Usage And Synthesis |
| Uses | 1,3-Bis(3-chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one (~90%) is an intermediate in the synthesis of 3’-[4-(5-Chloro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]propyl Domperidine (Domperidine Impurity F) (C365315), an impurity of the gastrokinetic and antinauseant drug Domperidone (D531100(P)), which is a novel peripheral dopamine receptor antagonist that does not cross the blood-brain barrier; anti-emetic. Domperidone(Motilium) is a dopamine blocker and an antidopaminergic reagent. |
| | Domperidone Impurity 15 Preparation Products And Raw materials |
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