1-Piperidinecarboxylic acid, 4-(3-butyn-1-yl)-, 1,1-dimethylethyl ester

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1-Piperidinecarboxylic acid, 4-(3-butyn-1-yl)-, 1,1-dimethylethyl ester Basic information
Product Name:1-Piperidinecarboxylic acid, 4-(3-butyn-1-yl)-, 1,1-dimethylethyl ester
Synonyms:1-Piperidinecarboxylic acid, 4-(3-butyn-1-yl)-, 1,1-dimethylethyl ester;tert-butyl 4-(but-3-ynyl)piperidine-1-carboxylate;tert-Butyl 4-(but-3-yn-1-yl)piperidine-1-carboxylate;Boc-Pip-butyn;4-(3-Butyn-1-yl)-1-Boc-piperidine;tert-butyl 4-(but-3-yn-1-yl)piperidine-1-carboxylate - [AC80617]
CAS:1346153-07-8
MF:C14H23NO2
MW:237.34
EINECS:
Product Categories:
Mol File:1346153-07-8.mol
1-Piperidinecarboxylic acid, 4-(3-butyn-1-yl)-, 1,1-dimethylethyl ester Structure
1-Piperidinecarboxylic acid, 4-(3-butyn-1-yl)-, 1,1-dimethylethyl ester Chemical Properties
form Oil
color Colorless to light yellow
Safety Information
MSDS Information
1-Piperidinecarboxylic acid, 4-(3-butyn-1-yl)-, 1,1-dimethylethyl ester Usage And Synthesis
UsesBoc-Pip-butyn is an Alkyl/ether-based PROTAC linker[1]. Boc-Pip-butyn is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Biological ActivityBoc-Pip-butyn is an Alkyl/ether-based PROTAC linker[1].
IC 50Alkyl/ether
References[1]. Yulu Zhou, et al. Photocatalytic Sulfonylcarbocyclization of Alkynes Using SEt as a Traceless Directing Group: Access to Cyclopentenes and Indenes. Angew Chem Int Ed Engl. 2022 Jan 3;61(1):e202110864.
1-Piperidinecarboxylic acid, 4-(3-butyn-1-yl)-, 1,1-dimethylethyl ester Preparation Products And Raw materials
Tag:1-Piperidinecarboxylic acid, 4-(3-butyn-1-yl)-, 1,1-dimethylethyl ester(1346153-07-8) Related Product Information
4-(but-3-yn-1-yl)piperidine hydrochloride tert-butyl 4-(prop-2-ynyl)piperidine-1-carboxylate 1-Boc-4-ethynylpiperidine tert-butyl 4-(pent-4-ynyl)piperidine-1-carboxylate tert-Butyl 4-(hex-5-yn-1-yl)piperidine-1-carboxylate tert-Butyl 4-(hept-6-yn-1-yl)piperidine-1-carboxylate