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| | Homodestcardin Basic information |
| Product Name: | Homodestcardin | | Synonyms: | Homodestcardin;Cyclo[N-methyl-L-alanyl-β-alanyl-(2R)-2-hydroxy-4-methylpentanoyl-(3S)-3-methyl-L-prolyl-L-isoleucyl-N-methyl-L-isoleucyl];cyclo[N-methyl-L-alanyl-beta-alanyl-(2R)-2-hydroxy-4-methylpentanoyl-(3S)-3-methyl-L-prolyl-L-isoleucyl-N-methyl-L-isoleucyl] | | CAS: | 917382-84-4 | | MF: | C32H55N5O7 | | MW: | 621.81 | | EINECS: | | | Product Categories: | | | Mol File: | 917382-84-4.mol |  |
| | Homodestcardin Chemical Properties |
| Boiling point | 879.1±65.0 °C(Predicted) | | density | 1.15±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Dichloromethane: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble | | form | A solid | | pka | 13.56±0.70(Predicted) |
| | Homodestcardin Usage And Synthesis |
| Uses | Homodestcardin, a destruxinbased cyclodepsipeptide, is a immunosuppressant. Homodestcardin, a fungal metabolite, displays pronounced activities against concanavalin A (Con A) activation, with an IC50 value of 0.86 μM[1]. | | IC 50 | Microbial Metabolite | | References | [1] Ai Hua Zhang, et al. Discovery of a new class of immunosuppressants from Trichothecium roseum co-inspired by cross-kingdom similarity in innate immunity and pharmacophore motif. Chem Asian J. 2013 Dec;8(12):3101-7. DOI:10.1002/asia.201300734 |
| | Homodestcardin Preparation Products And Raw materials |
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