N-desethyl Isotonitazene (hydrochloride)

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N-desethyl Isotonitazene (hydrochloride) Basic information
Product Name:N-desethyl Isotonitazene (hydrochloride)
Synonyms:N-desethyl Isotonitazene (hydrochloride)
CAS:
MF:
MW:0
EINECS:
Product Categories:
Mol File:Mol File
N-desethyl Isotonitazene (hydrochloride) Structure
N-desethyl Isotonitazene (hydrochloride) Chemical Properties
solubility DMF: 30 mg/ml
DMSO: 30 mg/ml
Ethanol: 30 mg/mlPBS (pH 7.2): 5 mg/ml
Safety Information
MSDS Information
N-desethyl Isotonitazene (hydrochloride) Usage And Synthesis
DescriptionN-desethyl Isotonitazene (hydrochloride) (Item No. 30216) is an analytical reference standard categorized as an opioid.1,2 N-desethyl Isotonitazene is a metabolite of isotonitazene (Item Nos. 30880 | 27255). N-desethyl Isotonitazene is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.WARNING This product is not for human or veterinary use.
References[1] ALEX J KROTULSKI. Isotonitazene Quantitation and Metabolite Discovery in Authentic Forensic Casework.[J]. Journal of analytical toxicology, 2020, 44 6: 521-530. DOI: 10.1093/jat/bkaa016
[2] MARTHE M. VANDEPUTTE. Synthesis, Chemical Characterization, and μ-Opioid Receptor Activity Assessment of the Emerging Group of “Nitazene” 2-Benzylbenzimidazole Synthetic Opioids.[J]. ACS Chemical Neuroscience, 2021. DOI: 10.22541/au.160520665.59016513/v2
[3] LAURA B KOZELL. Pharmacologic Characterization of Substituted Nitazenes at μ, κ, and Δ Opioid Receptors Suggests High Potential for Toxicity.[J]. Journal of Pharmacology and Experimental Therapeutics, 2024: 219-228. DOI: 10.1124/jpet.123.002052
[4] OMAYEMA TAOUSSI. Human metabolism of four synthetic benzimidazole opioids: isotonitazene, metonitazene, etodesnitazene, and metodesnitazene[J]. Archives of Toxicology, 2024, 98 7: 2101-2116. DOI: 10.1007/s00204-024-03735-0
[5] MENG-HUA M. TSAI, LEI SHI*   In Vitro Functional Profiling of Fentanyl and Nitazene Analogs at the μ-Opioid Receptor Reveals High Efficacy for Gi Protein Signaling[J]. ACS Chemical Neuroscience, 2024, 15 4: 854-867. DOI: 10.1021/acschemneuro.3c00750
[6] GRANT C GLATFELTER. Alkoxy chain length governs the potency of 2-benzylbenzimidazole “nitazene” opioids associated with human overdose.[J]. Psychopharmacology, 2023: 2573-2584. DOI: 10.1007/s00213-023-06451-2
[7] NICHOLAS J MALCOLM. Mu-opioid receptor selective superagonists produce prolonged respiratory depression.[J]. iScience, 2023, 26 7: 107121. DOI: 10.1016/j.isci.2023.107121
N-desethyl Isotonitazene (hydrochloride) Preparation Products And Raw materials
Tag:N-desethyl Isotonitazene (hydrochloride) Related Product Information
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