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| | APOLIPOPROTEIN E, ISOFORM E2, HUMAN, RECOMBINANT Basic information |
| Product Name: | APOLIPOPROTEIN E, ISOFORM E2, HUMAN, RECOMBINANT | | Synonyms: | HUMAN APOLIPOPROTEIN E2;HUMAN APOE2;APOLIPOPROTEIN E-II, HUMAN;APOLIPOPROTEIN E-II, HUMAN R-DNA;APOLIPOPROTEIN E, ISOFORM E2, HUMAN, RECOMBINANT;APOLIPOPROTEIN E, HUMAN;APOLIPOPROTEIN E2;APOLIPOPROTEIN E2 HUMAN | | CAS: | 456542-91-9 | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![APOLIPOPROTEIN E, ISOFORM E2, HUMAN, RECOMBINANT Structure]() |
| | APOLIPOPROTEIN E, ISOFORM E2, HUMAN, RECOMBINANT Chemical Properties |
| storage temp. | −20°C | | form | buffered aqueous solution | | biological source | human |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | APOLIPOPROTEIN E, ISOFORM E2, HUMAN, RECOMBINANT Usage And Synthesis |
| Uses | Apolipoprotein E, human has been used as a standard for the quantification of ApoE protein in the sucrose density gradient (SDG) fractions and the unfractionated brain homogenates using an in-house developed sandwich enzyme-linked immunosorbent assay (ELISA). It has also been used in western blotting to assess its exogenous effects on low-density lipoprotein (LDL)-heparin interactions. | | Biological Activity | In addition to facilitating solubilization of lipids, apolipoproteins help to maintain the structural integrity of lipoproteins, serve as ligands for lipoprotein receptors, and regulate the activity of enzymes involved in lipid metabolism. Apolipoprotein E (ApoE) plays an important role in lipid metabolism. It′s interaction with specific ApoE receptor enables uptake of chylomicron remnants by liver cells, which is an essential step during normal lipid metabolism. It also binds with the LDL receptor (Apo B/E). Defects in ApoE are a cause of hyperlipoproteinemia type III. |
| | APOLIPOPROTEIN E, ISOFORM E2, HUMAN, RECOMBINANT Preparation Products And Raw materials |
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