- 5-FLUORO-DL-TRYPTOPHAN
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- $15.00 / 1KG
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2021-08-12
- CAS:154-08-5
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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| | 5-FLUORO-DL-TRYPTOPHAN Basic information |
| | 5-FLUORO-DL-TRYPTOPHAN Chemical Properties |
| Melting point | 265 °C (dec.)(lit.) | | Boiling point | 450.7±45.0 °C(Predicted) | | density | 1.2556 (estimate) | | storage temp. | Keep in dark place,Inert atmosphere,2-8°C | | pka | 2.21±0.10(Predicted) | | form | powder | | color | white | | BRN | 22753 | | Major Application | detection peptide synthesis | | InChI | 1S/C11H11FN2O2/c12-7-1-2-10-8(4-7)6(5-14-10)3-9(13)11(15)16/h1-2,4-5,9,14H,3,13H2,(H,15,16) | | InChIKey | INPQIVHQSQUEAJ-UHFFFAOYSA-N | | SMILES | NC(Cc1c[nH]c2ccc(F)cc12)C(O)=O | | CAS DataBase Reference | 154-08-5(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/38 | | Safety Statements | 22-24/25 | | WGK Germany | 3 | | RTECS | YN6825000 | | Hazard Note | Irritant | | HS Code | 29339900 | | Storage Class | 11 - Combustible Solids |
| | 5-FLUORO-DL-TRYPTOPHAN Usage And Synthesis |
| Chemical Properties | light beige powder | | Uses | A metabolic antagonist of tryptophan | | Definition | ChEBI: A non-proteinogenic alpha-amino acid that is tryptophan in which the hydrogen at position 5 on the indole ring is replaced by a fluoro group. | | Biological Activity | 5-Fluoro-DL-tryptophan (5-F-TRP), a fluorine-containing analogue of tryptophan, may be incorporated into proteins such as cyclic AMP receptor protein (CRP) from Escherichia coli to study changes in ligand binding. 5-F-TRP may be used as an internal reference for chromatographic analysis of tryptophan and its derivatives found in whole blood. | | Purification Methods | Recrystallise it from EtOH, aqueous EtOH or AcOH. Also purify it by passage through a Dowex AG1x2 (acetate form) column and recrystallise the L-enantiomer (from enzymic enrichment) from H2O/EtOH, m 158-163o(dec), [] D -8.3o (c 2.5, N NaOH). [Coy et al. Biochemistry 13 3550 1974, Beilstein 22/14 V 116.] |
| | 5-FLUORO-DL-TRYPTOPHAN Preparation Products And Raw materials |
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