2',5'-DIDEOXYADENOSINE

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CAS:6698-26-6
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CAS:6698-26-6
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CAS:6698-26-6
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Products Intro: Product Name:2',5'-DIDEOXYADENOSINE
CAS:6698-26-6
Purity:98% Package:1g,10g,25g,100g,500g,1kg

2',5'-DIDEOXYADENOSINE manufacturers
2',5'-DIDEOXYADENOSINE Basic information
Product Name:2',5'-DIDEOXYADENOSINE
Synonyms:2',5'-DD-ADO;5-(6-AMINOPURIN-9-YL)-2-METHYLTETRAHYDROFURAN-3-OL;(2R,3S,5R)-5-(6-aMino-9H-purin-9-yl)-2-Methyltetrahydrofuran-3-ol;NSC 95943;NSC 95943 2',5'-DIDEOXYADENOSINE;phosphoric acid [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-2-oxolanyl]methyl [hydroxy(phosphonooxy)phosphoryl] [(2R,3S,4R,5R)-3,4,5,6-tetrahydroxy-1-oxohexan-2-yl] ester;2,5-Dideoxyadenosine - CAS 6698-26-6 - Calbiochem;Adenosine, 2',5'-dideoxy-
CAS:6698-26-6
MF:C10H13N5O2
MW:235.24
EINECS:
Product Categories:Adenylate cyclaseG Proteins and Cyclic Nucleotides;Adenylyl Cyclase Inhibitors;A to;Cyclic Nucleotide Metabolism;Enzyme Inhibitors by Enzyme
Mol File:6698-26-6.mol
2',5'-DIDEOXYADENOSINE Structure
2',5'-DIDEOXYADENOSINE Chemical Properties
Boiling point 547.0±60.0 °C(Predicted)
density 1.77±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO: soluble
form solid
pka14.06±0.60(Predicted)
color white
InChIInChI=1S/C10H13N5O2/c1-5-6(16)2-7(17-5)15-4-14-8-9(11)12-3-13-10(8)15/h3-7,16H,2H2,1H3,(H2,11,12,13)/t5-,6+,7-/m1/s1
InChIKeyFFHPXOJTVQDVMO-DSYKOEDSSA-N
SMILESC[C@H]1O[C@@H](N2C3C(=C(N=CN=3)N)N=C2)C[C@@H]1O
Safety Information
WGK Germany 3
HS Code 29349990
Storage Class11 - Combustible Solids
MSDS Information
ProviderLanguage
SigmaAldrich English
2',5'-DIDEOXYADENOSINE Usage And Synthesis
Chemical PropertiesWhite solid
Uses2′,5′-Dideoxyadenosine has been used to elucidate the mechanism of diligustilide (DLG). It has also been used to inhibit adenylate cyclase (AC).
Biochem/physiol ActionsCell-permeable adenylyl cyclase inhibitor. IC50 = 2.7 μM in detergent-dispersed rat brain preparations.
in vivo

2',5'-Dideoxyadenosine (0.1 mg/kg; IP; 15 min pre-treated) fully inhibits the diuretic, natriuretic and K+ and Cl- sparing effect of Fr EtOAc in rats[4].

Animal Model:Male Wistar rats (3-4 months old)[3]
Dosage:0.1 mg/kg
Administration:IP; 15 min pre-treated
Result:Fully inhibited the diuretic, natriuretic and K+ and Cl- sparing effect of FrEtOAc in rats.
2',5'-DIDEOXYADENOSINE Preparation Products And Raw materials
Tag:2',5'-DIDEOXYADENOSINE(6698-26-6) Related Product Information
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