| Company Name: |
Energy Chemical |
| Tel: |
400-0056266 |
| Email: |
marketing1@energy-chemical.com |
| Company Name: |
ACROBiosystems |
| Tel: |
13121935750 |
| Email: |
jiaxin.zhao@acrobiosystems.com |
|
| Product Name: | HUMAN HCC-1 | | Synonyms: | RECOMBINANT HUMAN HCC-1;HUMAN CCL14;HUMAN HCC-1;HUMAN HCC-3;HUMAN HEMOFILTRATE CC CHEMOKINE-1;HUMAN NCC-2;HEMOFILTRATE CC CHEMOKINE-1 HUMAN;HEPATO CELLULAR CARCINOMA-1, HUMAN | | CAS: | 169146-44-5 | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![HUMAN HCC-1 Structure]() |
| | HUMAN HCC-1 Chemical Properties |
| storage temp. | −20°C | | form | lyophilized powder | | color | white to off-white | | biological source | human |
| WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | HUMAN HCC-1 Usage And Synthesis |
| Biological Activity | HCC-1, a member of the C-C, or β chemokine class, is a 8.7 kDa, non-glycosylated polypeptide of 74 amino acids. Mature HCC-1 is produced by cleavage of a 19 amino acid signal peptide from the precursor HCC-1 (93 amino acids). HCC-1 is expressed constitutively in normal tissues and is present in high concentrations in human plasma. It shows approximately 46% amino acid identity with MIP-1α and MIP-1β, and 29-37% sequence identity with other C-C chemokines. | | Description | HCC-1 Human Recombinant produced in E.Coli is a single,non-glycosylated, polypeptide chain containing 72 amino acids and having a molecular mass of 8411 Dalton.
The HCC-1 is purified by proprietary chromatographic techniques. | | Source | Escherichia Coli | | Background | Chemokine (C-C motif) ligand 14 (CCL14) is a small cytokine belonging to the CC chemokine family. It is also commonly known as HCC-1. It is produced as a protein precursor that is procesed to generate a mature active protein containing 74 amino acids that and is 46% identical in amino acid composition to CCL3 and CCL4. This chemokine is expressed in various tissues including spleen, bone marrow, liver, muscle, and gut. CCL13 activates monocytes, but does not induce their chemotaxis. Human CCL13 is located on chromosome 17 within a cluster of other chemokines belonging to the CC family. |
| | HUMAN HCC-1 Preparation Products And Raw materials |
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