9-Phenyl-2,4-bis(trifluoromethyl)[1,2,4]triazolo[4,3-a][1,8]naphthyridine manufacturers
- 5M038
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- $1520.00
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2026-07-27
- CAS:338962-32-6
- Purity:
- Supply Ability: 10g
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| | 9-Phenyl-2,4-bis(trifluoromethyl)[1,2,4]triazolo[4,3-a][1,8]naphthyridine Basic information |
| Product Name: | 9-Phenyl-2,4-bis(trifluoromethyl)[1,2,4]triazolo[4,3-a][1,8]naphthyridine | | Synonyms: | [1,2,4]Triazolo[4,3-a][1,8]naphthyridine, 9-phenyl-2,4-bis(trifluoromethyl)-;5M038;5M-038,5M038;9-Phenyl-2,4-bis(trifluoromethyl)[1,2,4]triazolo[4,3-a][1,8]naphthyridine | | CAS: | 338962-32-6 | | MF: | C17H8F6N4 | | MW: | 382.26 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![9-Phenyl-2,4-bis(trifluoromethyl)[1,2,4]triazolo[4,3-a][1,8]naphthyridine Structure](StructureFile/ChemBookStructure3/GIF/CB0696043.gif) |
| | 9-Phenyl-2,4-bis(trifluoromethyl)[1,2,4]triazolo[4,3-a][1,8]naphthyridine Chemical Properties |
| density | 1.55±0.1 g/cm3(Predicted) | | pka | -1.13±0.50(Predicted) |
| | 9-Phenyl-2,4-bis(trifluoromethyl)[1,2,4]triazolo[4,3-a][1,8]naphthyridine Usage And Synthesis |
| Uses | 5M038 is an inhibitor of HIV envelope-mediated fusion with potent inhibitory activity against gp41-mediated membrane fusion. 5M038 prevents the formation of the gp41 post-fusion conformation and inhibits envelope-mediated membrane fusion in cell-cell fusion and viral infectivity assays. 5M038 has shown broad fusion inhibition in tests against multiple HIV-1 subtypes, including M and T strains. 5M038 targets a highly conserved hydrophobic pocket and binds to the gp41 trimer, thereby exerting its inhibitory effect[1]. | | References | [1] Small molecules that bind the inner core of gp41 and inhibit HIV envelope-mediated fusion |
| | 9-Phenyl-2,4-bis(trifluoromethyl)[1,2,4]triazolo[4,3-a][1,8]naphthyridine Preparation Products And Raw materials |
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