- 3-Iodobenzaldehyde
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- $2.00 / 100kg
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2025-07-18
- CAS:696-41-3
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 100kg
- 3-Iodobenzaldehyde
-
- $0.00 / 1KG
-
2025-04-04
- CAS:696-41-3
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 1ton
- 3-Iodobenzaldehyde
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- $0.00 / 1g
-
2025-01-03
- CAS:696-41-3
- Min. Order: 10mg
- Purity: 99%HPLC
- Supply Ability: 2000tons
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| | 3-Iodobenzaldehyde Basic information |
| | 3-Iodobenzaldehyde Chemical Properties |
| Melting point | 57-60 °C (lit.) | | Boiling point | 124-125°C 13mm | | density | 1.8576 (estimate) | | Fp | 124-125°C/13mm | | storage temp. | 2-8°C | | form | Crystalline Powder, Crystals or Needles | | color | White to pale yellow | | Water Solubility | Slightly soluble in water. | | Sensitive | Air & Light Sensitive | | BRN | 1854653 | | InChIKey | RZODAQZAFOBFLS-UHFFFAOYSA-N | | CAS DataBase Reference | 696-41-3(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | Hazard Note | Irritant | | HazardClass | IRRITANT, AIR SENSITIVE, KEEP COLD | | HS Code | 29130000 |
| | 3-Iodobenzaldehyde Usage And Synthesis |
| Chemical Properties | Pale yellow crystalline powder | | Uses | 3-Iodobenzaldehyde is used as an organic reagent. | | General Description | 3-Iodobenzaldehyde can be prepared by the iodination of benzaldehyde using 1,3-diiodo-5,5-dimethylhydantoin in sulfuric acid. | | Synthesis | 3-Iodobenzaldehyde (12) was synthesized as follows: pyridinium chlorochromate (2.45 g, 11.4 mmol) and dry diatomaceous earth (about 2.00 g) were suspended in anhydrous dichloromethane (20 ml) at room temperature and stirred for 15 minutes. Subsequently, a solution of 3-iodobenzyl alcohol (11) (1.02 g, 4.35 mmol) in anhydrous dichloromethane (5 ml) was added to this suspension. The reaction mixture was protected from light and stirring was continued for 2 hours at room temperature. After completion of the reaction, the reaction solution was diluted with ether and filtered through diatomaceous earth. The resulting turbid brown filtrate was concentrated to a reddish brown gelatinous paste, which was redissolved in dichloromethane and purified by short silica gel column chromatography using dichloromethane as eluent. A clarified colorless solution was finally obtained, and 3-iodobenzaldehyde (12) was concentrated to give 3-iodobenzaldehyde (12) as a white solid (0.953 g, 95% yield).1H NMR (400 MHz, CDCl3) data were as follows: δ 7.29 (t, J = 7.8 Hz, 1H, H5); 7.85 (br d, J = 7.8 Hz, 1H, H6); 7.96 (br d, J =7.8 Hz, 1H, H4); 8.21 (br s, 1H, H2); 9.93 (s, 1H, CHO). | | References | [1] Advanced Synthesis and Catalysis, 2004, vol. 346, # 7, p. 767 - 776
[2] Patent: WO2005/82894, 2005, A1. Location in patent: Page/Page column 41-42
[3] Bulletin of the Chemical Society of Ethiopia, 2013, vol. 27, # 1, p. 131 - 136
[4] Bioorganic and Medicinal Chemistry Letters, 1999, vol. 9, # 20, p. 3047 - 3052
[5] Tetrahedron Asymmetry, 2001, vol. 12, # 4, p. 585 - 596 |
| | 3-Iodobenzaldehyde Preparation Products And Raw materials |
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