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| Product Name: | MOUSE TNF-ALPHA | | Synonyms: | MURINE TNF-ALPHA;EXTRACELLULAR DOMAIN (AA 77-235), MOUSE;CACHECTIN;MURINE TNFSF2;MURINE TUMOR NECROSIS FACTOR ALPHA;MOUSE TUMOR NECROSIS FACTOR ALPHA;MOUSE TNF-ALPHA;MOUSE TNF-ALPHA (E COLI-DERIVED) | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![MOUSE TNF-ALPHA Structure]() |
| | MOUSE TNF-ALPHA Chemical Properties |
| storage temp. | 2-8°C | | form | powder |
| | MOUSE TNF-ALPHA Usage And Synthesis |
| Description | Tumor Necrosis Factor-a Mouse Recombinant produced in E. coli is a single, non glycosylated, polypeptide chain containing 157 amino acids and having a molecular mass of 17301.32 Dalton.
The TNF-alpha is purified by standard chromatographic techniques. | | Source | Escherichia Coli | | Background | Tumor necrosis factor is a cytokine involved in systemic inflammation and is a member of a group of cytokines that all stimulate the acute phase reaction. TNF is mainly secreted by macrophages.
TNF causes apoptotic cell death, cellular proliferation, differentiation, inflammation, tumorigenesis and viral replication, TNF is also involved in lipid metabolism, and coagulation. TNF's primary role is in the regulation of immune cells.
Dysregulation and, in particular, overproduction of TNF have been implicated in a variety of human diseases- autoimmune diseases, insulin resistance, and cancer. |
| | MOUSE TNF-ALPHA Preparation Products And Raw materials |
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