- Dictamine
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- $45.00
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2026-06-02
- CAS:484-29-7
- Purity: 99.88%
- Supply Ability: 10g
- Dictamnine
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-
2023-02-24
- CAS:484-29-7
- Min. Order: 5mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
- DICTAMNINE
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- $15.00
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2021-07-02
- CAS:484-29-7
- Min. Order: 1KG
- Purity: 99%+ HPLC
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| | DICTAMNINE Basic information |
| | DICTAMNINE Chemical Properties |
| Melting point | 133° | | Boiling point | 336.72°C (rough estimate) | | density | 1.1919 (rough estimate) | | refractive index | 1.5880 (estimate) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | Chloroform (Slightly), Methanol (Slightly, Heated) | | pka | 7.24±0.40(Predicted) | | form | Solid | | color | Light Beige | | CAS DataBase Reference | 484-29-7 |
| | DICTAMNINE Usage And Synthesis |
| Chemical Properties | Soluble in hot ethanol and chloroform, slightly soluble in ether, and insoluble in water. It comes from the root of Dictamnus dasycarpus Turcz., a plant of the Rutaceae family. | | Uses | antifungal, vasal relaxant, mooth muscle contractant | | Uses | Dictamnine is an herbal extract from the root of Dictamnus dasycarpus, and exhibits anti-microbial activity against bacteria and fungi. Phytotoxic agent. | | Definition | ChEBI: Dictamnine is an oxacycle, an organonitrogen heterocyclic compound, an organic heterotricyclic compound and an alkaloid antibiotic. | | Synthesis Reference(s) | Tetrahedron Letters, 14, p. 843, 1973 DOI: 10.1016/S0040-4039(01)95731-4 | | in vivo | Dictamine (2 μg/mL, 200 μL, applied once daily, for 14 days) reduces skin inflammation and skin swellingin Oxazolone (HY-126360)-induced atopic dermatitis mice model[2].
Dictamine (50 and 100 mg/kg, p.o., three times a week) inhibits tumor growth in a HCT116 xenograft tumor model[3].
Dictamine (1 and 5 mg/kg, 200 μL, applied to the skin) ameliorates chronic itch in 2,4-dinitrofluorobenzene-induced atopic dermatitis mice[4].
| Animal Model: | HCT116 xenograft tumor model[3] | | Dosage: | 50 and 100 mg/kg | | Administration: | p.o., three times a week | | Result: | Inhibited tumor growth.
Reduced HIF-1α and Slug protein level in the tumor tissue. |
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| | DICTAMNINE Preparation Products And Raw materials |
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