- 2-Iodoadenosine
-
- $0.00 / 100mg
-
2025-08-21
- CAS:35109-88-7
- Min. Order:
- Purity:
- Supply Ability: 10g
- 2-IODOADENOSINE
-
- $0.00 / 25kg
-
2025-07-25
- CAS:35109-88-7
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1000kg
- 2-IODOADENOSINE
-
- $15.00 / 1KG
-
2021-08-12
- CAS:35109-88-7
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
|
| | 2-IODOADENOSINE Basic information |
| Product Name: | 2-IODOADENOSINE | | Synonyms: | 2-Iodo-D-adenosine;(2R,3R,4R,5R)-2-(6-AMINO-2-IODO-PURIN-9-YL)-5-(HYDROXYMETHYL)OXOLANE-3,4-DIOL(2-IODOADENOSINE);2-IODOADENOSINE;6-Amino-2-iodo-9-(beta-D-ribofuranosyl)purine;(2R,3R,4S,5R)-2-(6-aMino-2-iodo-9H-purin-9-yl)-5-(hydroxyMethyl)tetrahydrofuran-3,4-diol;(4S,2R,3R,5R)-2-(6-amino-2-iodopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol;2-Iodoadenosine>;Adenosine, 2-iodo- | | CAS: | 35109-88-7 | | MF: | C10H12IN5O4 | | MW: | 393.14 | | EINECS: | 623-798-8 | | Product Categories: | Carbohydrates & Derivatives;Intermediates & Fine Chemicals;Pharmaceuticals;Nucleotides and Nucleosides;Bases & Related Reagents;Nucleotides;Nucleosides;Oligonucleotide Synthesis;Specialty Synthesis | | Mol File: | 35109-88-7.mol |  |
| | 2-IODOADENOSINE Chemical Properties |
| Melting point | 200 °C (dec.) | | Boiling point | 776.3±70.0 °C(Predicted) | | density | 2.69±0.1 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | DMSO, Methanol, Water | | form | Solid | | pka | 13.05±0.70(Predicted) | | color | Off-White to Pale Yellow | | λmax | 265nm(H2O)(lit.) | | InChIKey | MGEBVSZZNFOIRB-UUOKFMHZSA-N | | CAS DataBase Reference | 35109-88-7(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26 | | WGK Germany | 3 | | HS Code | 29349990 |
| | 2-IODOADENOSINE Usage And Synthesis |
| Description | 2-Iodoadenosine is a chemical compound that is produced from the oxidation of uridine. It is used in the synthesis of peptides, which are important for biological processes like signal transduction and cell growth. | | Chemical Properties | Off-White Crystalline Solid | | Synthesis | GENERAL STEPS: To a flask containing 6.0 g (11.1 mmol) of (2R,3R,4R,5R)-2-(acetyloxymethyl)-5-(6-chloro-2-iodo-9H-purin-9-yl)tetrahydrofuran-3,4-diyldiacetate was added 100 mL of liquid NH3 at -78 °C with continuous stirring for 6 hours. Subsequently, the reaction mixture was slowly warmed to room temperature and the NH3 was evaporated overnight to give a brown oil. The product was purified by hot isopropanol crystallization to give 2-iodoadenosine (80% yield, melting point 143-145°C). Thin layer chromatographic analysis (20% MeOH/CHCl3) showed an Rf value of 0.6. 1H NMR (300 MHz, DMSO-d6) δ 8.24 (s, 1H), 7.68 (s, 2H), 5.75 (d, J = 6.16 Hz, 1H), 5.42 (d, J = 5.40 Hz, 1H), 5.16 (d, J = 4.62 Hz , 1H), 4.99 (t, J = 5.39 Hz, 1H), 4.67 (d, J = 4.81 Hz, 1H), 4.06 (d, J = 3.37 Hz, 1H), 3.89 (m, 1H), 3.54 (m, 2H). | | References | [1] Journal of Organic Chemistry, 1985, vol. 50, # 3, p. 406 - 408
[2] Chemical and Pharmaceutical Bulletin, 1985, vol. 33, # 4, p. 1766 - 1769
[3] Journal of Organic Chemistry, 1988, vol. 53, # 13, p. 3051 - 3057
[4] Journal of Medicinal Chemistry, 1992, vol. 35, # 2, p. 241 - 252
[5] Patent: US4956345, 1990, A |
| | 2-IODOADENOSINE Preparation Products And Raw materials |
|