6-AMINO-N-CYCLOHEXYL-3-METHYLTHIAZOLO[3,2-A]BENZIMIDAZOLE-2-CARBOXAMIDE HYDROCHLORIDE
| 中文名称 | 6-AMINO-N-CYCLOHEXYL-3-METHYLTHIAZOLO[3,2-A]BENZIMIDAZOLE-2-CARBOXAMIDE HYDROCHLORIDE |
|---|---|
| 中文同义词 | DESMETHYL YM298198 HYDROCHLORIDE,ANALOGUE OF MGLU1拮抗剂YM298198 |
| 英文名称 | 6-AMINO-N-CYCLOHEXYL-3-METHYLTHIAZOLO[3,2-A]BENZIMIDAZOLE-2-CARBOXAMIDE HYDROCHLORIDE |
| 英文同义词 | DESMETHYL-YM 298198;6-AMINO-N-CYCLOHEXYL-3-METHYLTHIAZOLO[3,2-A]BENZIMIDAZOLE-2-CARBOXAMIDE HYDROCHLORIDE;Desmethyl-YM 298198 hydrochloride;Thiazolo[3,2-a]benzimidazole-2-carboxamide,6-amino-N-cyclohexyl-3-methyl-;Desmethyl YM298198 hydrochloride, Analogue of mGlu1 antagonist YM298198 |
| CAS号 | 299901-57-8 |
| 分子式 | C17H20N4OS |
| 分子量 | 328.43 |
| EINECS号 | |
| 相关类别 | Glutamate receptor;Glutamate |
| Mol文件 | 299901-57-8.mol |
| 结构式 | ![6-AMINO-N-CYCLOHEXYL-3-METHYLTHIAZOLO[3,2-A]BENZIMIDAZOLE-2-CARBOXAMIDE HYDROCHLORIDE 结构式](CAS/GIF/299901-57-8.gif) |
6-AMINO-N-CYCLOHEXYL-3-METHYLTHIAZOLO[3,2-A]BENZIMIDAZOLE-2-CARBOXAMIDE HYDROCHLORIDE 性质
| 储存条件 | Desiccate at RT |
|---|
Desmethyl-YM-298198 是一种高亲和力、选择性、非竞争性 mGluR1 拮抗剂 (IC50: 16 nM)。Desmethyl-YM-298198 对 Streptozotocin (HY-13753) 诱导的痛觉过敏小鼠具有镇痛作用。