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| | 1H-INDOLE-6-METHANAMINE Basic information |
| | 1H-INDOLE-6-METHANAMINE Chemical Properties |
| Melting point | 135-140℃ | | Boiling point | 335.6±17.0 °C(Predicted) | | density | 1.199±0.06 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | form | solid | | pka | 17.21±0.30(Predicted) | | Appearance | Off-white to light yellow Solid | | Water Solubility | Slightly soluble in water. | | Sensitive | Moisture Sensitive | | InChI | 1S/C9H10N2/c10-6-7-1-2-8-3-4-11-9(8)5-7/h1-5,11H,6,10H2 | | InChIKey | FURRUNQWZZOXOT-UHFFFAOYSA-N | | SMILES | NCc1ccc2cc[nH]c2c1 | | CAS DataBase Reference | 3468-17-5 |
| Hazard Codes | Xi,Xn | | Risk Statements | 22-37/38-41 | | Safety Statements | 26-39 | | WGK Germany | 3 | | HazardClass | IRRITANT | | HS Code | 2933998090 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral
Eye Dam. 1
Skin Irrit. 2
STOT SE 3 |
| | 1H-INDOLE-6-METHANAMINE Usage And Synthesis |
| Uses | 6-(Aminomethyl)indole is used as an organic chemical synthesis intermediate. | | Synthesis | Example 71 Preparation of 1H-indole-6-methylamine: 1H-indole-6-carbonitrile (prepared by literature methods: Batcho, AD; Leimgruber, W. Organic Syntheses 1985, 63, 214-225; 1.50 g, 10.6 mmol) was hydrogenated overnight at atmospheric pressure over a nickel Nguyenne catalyst in a mixture of ethanol (50 mL) and concentrated ammonia (4 mL). (4 mL) in a mixed solution of ethanol (50 mL) and concentrated ammonia (4 mL) at atmospheric pressure overnight for hydrogenation. Upon completion of the reaction, the reaction mixture was filtered through Celite to remove the catalyst. The filter cake was washed well with ethanol, taking care to avoid drying of the catalyst. The filtrates were combined and concentrated to afford 1H-indole-6-methylamine (1.50 g, 97% yield). | | References | [1] Patent: US2002/161237, 2002, A1 |
| | 1H-INDOLE-6-METHANAMINE Preparation Products And Raw materials |
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