- Tetrahydro-4-pyranol
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- $0.00 / 200KG
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2026-03-21
- CAS:2081-44-9
- Min. Order: 1KG
- Purity: ≥98%
- Supply Ability: 100mt/year
- Tetrahydro-4-pyranol
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- $0.00 / 25KG
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2026-03-20
- CAS:2081-44-9
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10 mt
- Tetrahydro-4-pyranol
-
- $0.00 / 1KG
-
2026-03-20
- CAS:2081-44-9
- Min. Order: 1KG
- Purity: 99%min
- Supply Ability: 30tons/month
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| | Tetrahydro-4-pyranol Basic information |
| | Tetrahydro-4-pyranol Chemical Properties |
| Boiling point | 87 °C/15 mmHg (lit.) | | density | 1.071 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.462(lit.) | | Fp | 190 °F | | storage temp. | Sealed in dry,Room Temperature | | solubility | Chloroform, Methanol | | pka | 14.61±0.20(Predicted) | | form | Oil | | color | Clear Colourless | | BRN | 102736 | | InChI | InChI=1S/C5H10O2/c6-5-1-3-7-4-2-5/h5-6H,1-4H2 | | InChIKey | LMYJGUNNJIDROI-UHFFFAOYSA-N | | SMILES | C1OCCC(O)C1 | | LogP | -0.440 (est) | | CAS DataBase Reference | 2081-44-9(CAS DataBase Reference) | | NIST Chemistry Reference | Tetrahydro-4H-pyran-4-ol(2081-44-9) |
| Hazard Codes | Xi,Xn | | Risk Statements | 41-36/37/38-20/22 | | Safety Statements | 26-39-36/37/39-23 | | RIDADR | 1993 | | WGK Germany | 3 | | HazardClass | IRRITANT | | HS Code | 29329990 | | Storage Class | 10 - Combustible liquids | | Hazard Classifications | Eye Dam. 1 |
| | Tetrahydro-4-pyranol Usage And Synthesis |
| Chemical Properties | Colorless transparent liquid | | Uses | Tetrahydro-4-pyranol (4-Hydroxytetrahydropyran) was used in the quantitative analysis of 3-hydroxytetrahydropyran (3-HTHP). | | Uses | Tetrahydro-4-pyranol is a building block of various organic compounds and pharmaceuticals. | | Synthesis | General procedure for the synthesis of tetrahydropyran-4-ol from tetrahydropyranone: To a tetrahydrofuran (THF, 25 mL) solution of tetrahydropyranone (5.0 g, 50 mmol), which was cooled to 0 °C, a THF (50 mL) suspension of lithium aluminum hydride (LiAlH4, 3.8 g, 0.1 mol) was slowly added. The reaction mixture was stirred at 0 °C for 30 min, followed by sequential addition of water (3.8 mL), 15% aqueous sodium hydroxide (NaOH) solution (3.8 mL) and water (11.4 mL) to quench the reaction. The mixture was filtered and the solid was washed with ethyl acetate (70 mL x 2). The filtrates were combined and evaporated to give tetrahydropyran-4-ol (5.09 g, 99% yield). | | References | [1] Patent: WO2008/88881, 2008, A1. Location in patent: Page/Page column 39
[2] Patent: US9301951, 2016, B2. Location in patent: Page/Page column 125
[3] Chemistry - A European Journal, 2018, vol. 24, # 62, p. 16526 - 16531
[4] Patent: US2010/76029, 2010, A1. Location in patent: Page/Page column 35
[5] Patent: US2011/71196, 2011, A1. Location in patent: Page/Page column 18-19 |
| | Tetrahydro-4-pyranol Preparation Products And Raw materials |
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