- 3,4-Dichloroiodobenzene
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- $101.00 / 1KG
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2025-09-25
- CAS:20555-91-3
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
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| | 3,4-Dichloroiodobenzene Basic information |
| Product Name: | 3,4-Dichloroiodobenzene | | Synonyms: | Benzene,1,2-dichloro-4-iodo-;3,4-Dichloro-1-iodobenzene;3,4-Dichlorophenyl iodide;4-Iodo-o-dichlorobenzene;3,4-Dichloroiodobenzene,98%;3,4-Dichloroiodobenzene 99%;3,4-Dichloroiodobenzene(1,2-Dichloro-4-iodobenzene);1,2-DICHLORO-4-IODOBENZENE | | CAS: | 20555-91-3 | | MF: | C6H3Cl2I | | MW: | 272.9 | | EINECS: | 243-874-0 | | Product Categories: | Aryl;Building Blocks;Chemical Synthesis;Halogenated Hydrocarbons;Organic Building Blocks;Chlorine Compounds;Iodine Compounds;C6 | | Mol File: | 20555-91-3.mol |  |
| | 3,4-Dichloroiodobenzene Chemical Properties |
| Melting point | 27-29 °C (lit.) | | Boiling point | 116-118 °C (12 mmHg) | | density | 1.9882 (estimate) | | refractive index | 1.6480 | | Fp | >230 °F | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | soluble in Methanol | | form | powder to lump to clear liquid | | color | White or Colorless to Yellow | | Sensitive | Light Sensitive | | BRN | 2245136 | | InChI | 1S/C6H3Cl2I/c7-5-2-1-4(9)3-6(5)8/h1-3H | | InChIKey | NADPFZNWCQIJJW-UHFFFAOYSA-N | | SMILES | Clc1ccc(I)cc1Cl | | CAS DataBase Reference | 20555-91-3(CAS DataBase Reference) | | EPA Substance Registry System | Benzene, 1,2-dichloro-4-iodo- (20555-91-3) |
| Hazard Codes | Xi,Xn | | Risk Statements | 36/37/38-20/21/22 | | Safety Statements | 37/39-26-36/37/39 | | WGK Germany | 3 | | Hazard Note | Irritant/Light Sensitive | | TSCA | TSCA listed | | HS Code | 29039990 | | Storage Class | 11 - Combustible Solids |
| | 3,4-Dichloroiodobenzene Usage And Synthesis |
| Chemical Properties | beige low melting solid | | Uses | 3,4-Dichloroiodobenzene may be used in the preparation of:
- tetrachloromethoxybiphenyls
- 1-(3,4-dichlorophenyl)-2-trimethylsilylacetylene
- 2-(3,4-dichlorocinnamyl)isoindoline-1,3-dione
| | General Description | 3,4-Dichloroiodobenzene undergoes Stille coupling reaction with vinyltributyltin in the presence of Pd(0)precursors to furnish styrene derivative. | | Synthesis | General procedure for the synthesis of 3,4-dichloroiodobenzene from 3,4-dichloroaniline: 3,4-dichloroaniline (15 g) was added to a stirred aqueous solution (350 mL) of concentrated H2SO4 (27.2 g). The mixture was heated to 80°C and stirred at this temperature for 10 minutes. Subsequently, the mixture was cooled to below 5°C and an aqueous solution of NaNO2 (6.4 g) (40 mL) was slowly added dropwise. After the dropwise addition, stirring was continued for 1 hour, and then an aqueous solution of KI (15.4 g) (40 mL) was slowly added. The reaction mixture was stirred for an additional 30 min, followed by heating in a 40 °C water bath for 30 min. After the reaction was completed, the mixture was extracted with CH2Cl2. The CH2Cl2 extracts were combined, dried and concentrated with CaCl2. Finally, the residue was purified by column chromatography using petroleum ether as eluent to give 20 g of the target product 3,4-dichloroiodobenzene in 79% yield. | | References | [1] Patent: US2005/234046, 2005, A1. Location in patent: Page/Page column 59
[2] Recueil des Travaux Chimiques des Pays-Bas, 1930, vol. 49, p. 1082,1087
[3] Journal of Organometallic Chemistry, 1977, vol. 136, p. 185 - 200
[4] Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1982, p. 1593 - 1598 |
| | 3,4-Dichloroiodobenzene Preparation Products And Raw materials |
| Raw materials | 3,4-Dichloroaniline-->Sulfuric acid-->Sodium nitrite-->Potassium iodide | | Preparation Products | 2',3,4-TRICHLOROBIPHENYL-->3,3',4,4'-TETRACHLOROBIPHENYL-->5-(3,4-Dichlorophenyl)furfural-->Benzeneacetic acid, 3,4-dichloro-α-methylene-, methyl ester-->(S)-2-(3,4-dichlorobenzyl)pyrrolidine-->Benzenepropanal, 3,4-dichloro- |
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