- Acetophenone oxime
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- $2.00
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2019-12-23
- CAS:613-91-2
- Min. Order: 1KG
- Purity: ≥98%
- Supply Ability: 100kg
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| | Acetophenone oxime Basic information |
| | Acetophenone oxime Chemical Properties |
| Melting point | 55-60 °C (lit.) | | Boiling point | 118-120 °C/20 mmHg (lit.) | | density | 1.11 g/mL at 25 °C (lit.) | | refractive index | 1.5302 (rough estimate) | | Fp | 118-120°C/20mm | | storage temp. | -20°C | | pka | 11.43±0.70(Predicted) | | form | powder to crystal | | color | White to Light yellow | | Water Solubility | slightly soluble | | Sensitive | Air & Moisture Sensitive | | BRN | 1562059 | | InChI | 1S/C8H9NO/c1-7(9-10)8-5-3-2-4-6-8/h2-6,10H,1H3/b9-7+ | | InChIKey | JHNRZXQVBKRYKN-CLFYSBASSA-N | | SMILES | C\C(=N/O)c1ccccc1 | | CAS DataBase Reference | 613-91-2(CAS DataBase Reference) | | NIST Chemistry Reference | Ethanone, 1-phenyl-, oxime(613-91-2) | | EPA Substance Registry System | Ethanone, 1-phenyl-, oxime (613-91-2) |
| Hazard Codes | T,Xi | | Risk Statements | 25-41-36/37/38 | | Safety Statements | 26-39-37/39 | | RIDADR | UN 2811 6.1/PG 3 | | WGK Germany | 3 | | RTECS | AM9654000 | | TSCA | TSCA listed | | HazardClass | IRRITANT | | HS Code | 29280090 | | Storage Class | 11 - Combustible Solids | | Toxicity | LD50 orl-mus: 2 g/kg MEXPAG 11,137,64 |
| | Acetophenone oxime Usage And Synthesis |
| Description | Acetophenone oxime is a solid but slightly soluble substance. Acetophenone oxime is incompatible with strong oxidising agents, moisture, acids, and metal and alkali compounds. Acetophenone oxime on decomposition releases irritating and toxic fumes and gases. There is no published data about the hazardous polymerisation of acetophenone oxime. | | Chemical Properties | Acetophenone oxime is a solid but slightly soluble substance. It is incompatible with strong
oxidizing agents, moisture, acids, metal, and alkali compounds. On decomposition, acetophenone
oxime releases irritating and toxic fumes and gases. There are no published data
about the hazardous polymerization of acetophenone oxime. | | Chemical Properties | WHITE TO CREAM CRYSTALLINE POWDER | | Uses | 1-Phenylethanone Oxime is a useful reagent for organic synthesis | | Synthesis Reference(s) | The Journal of Organic Chemistry, 52, p. 5089, 1987 DOI: 10.1021/jo00232a005
Tetrahedron Letters, 30, p. 5763, 1989 DOI: 10.1016/S0040-4039(00)76191-0 | | Health Hazard | Exposures to acetophenone oxime cause irritation to the eyes, skin, and the respiratory
and digestive tracts. The toxicological properties of acetophenone oxime are not been fully
investigated. | | Safety Profile | Poison by an unspecified route.Slightly toxic by ingestion. When heated to decomposition itemits toxic vapors of NOx. | | Synthesis | Add 6.4 ml (55 mmol) of acetophenone, 6 g (86 mmol) of hydroxylamine hydrochloride,4 ml of freshly distilled water and 20 ml of 95% ethanol to the reaction flask, and add 11 g (275 mmol) of solid sodium hydroxide in a batch in an ice bath, at which time the solution becomes a white turbid liquid, reflux at elevated temperature for five minutes, and then, after cooling, the solution is poured into a beaker containing 30 ml of concentrated hydrochloric acid and 200 ml of After cooling, the solution was poured into a beaker containing 30 ml of concentrated hydrochloric acid and 200 ml of water to obtain a white solid acetophenone oxime with a melting point of 58 C to 60 C. | | storage | Acetophenone oxime should be kept stored in a cool, dry place and in a closed container
when not in use. | | Precautions | On exposures to acetophenone oxime, occupational workers should immediately fl ush the
eyes with plenty of water. Workers should use proper personal protective equipment, wear
appropriate gloves to prevent skin exposure, and wear appropriate protective eyeglasses
or chemical safety goggles as described. |
| | Acetophenone oxime Preparation Products And Raw materials |
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