Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-7-hydroxy-3-(hydroxymethyl)-, (3S,7R,8aS)- manufacturers
- JBP485
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- $1520.00
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2026-04-21
- CAS:211868-63-2
- Purity:
- Supply Ability: 10g
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| | Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-7-hydroxy-3-(hydroxymethyl)-, (3S,7R,8aS)- Basic information |
| Product Name: | Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-7-hydroxy-3-(hydroxymethyl)-, (3S,7R,8aS)- | | Synonyms: | Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-7-hydroxy-3-(hydroxymethyl)-, (3S,7R,8aS)- | | CAS: | 211868-63-2 | | MF: | C8 H12 N2 O4 | | MW: | 200.19 | | EINECS: | | | Product Categories: | | | Mol File: | 211868-63-2.mol | ![Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-7-hydroxy-3-(hydroxymethyl)-, (3S,7R,8aS)- Structure](CAS/20200611/GIF/211868-63-2.gif) |
| | Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-7-hydroxy-3-(hydroxymethyl)-, (3S,7R,8aS)- Chemical Properties |
| Cosmetics Ingredients Functions | SKIN CONDITIONING - EMOLLIENT HUMECTANT SKIN CONDITIONING |
| | Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-7-hydroxy-3-(hydroxymethyl)-, (3S,7R,8aS)- Usage And Synthesis |
| Description | JBP485 is an inhibitor of renal transporters OAT1 and OAT3. JBP485 is an antihepatitis agent as a substrate for intestinal PEPT1. | | Uses | JBP485 (cyclo-trans-4-L-hydroxyprolyl-L-serine) is a dipeptide with anti-hepatotoxic and wound healing properties. JBP485 can be used for research of various kinds of corneal epithelial diseases[1]. | | in vivo | JBP485 (100 μM, topical application, 4 times per day) accelerates the corneal epithelial wound healing on rabbits (4 days for healing completely, compared with 5 days for control group)[1].
| | References | [1] Nagata M, et al. JBP485 promotes corneal epithelial wound healing. Sci Rep. 2015 Oct 1;5:14776. DOI:10.1038/srep14776 |
| | Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-7-hydroxy-3-(hydroxymethyl)-, (3S,7R,8aS)- Preparation Products And Raw materials |
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