Aminooxy-PEG8-acid manufacturers
- Aminooxy-PEG8-acid
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2025-06-07
- CAS:2055269-60-6
- Min. Order: 50mg
- Purity: >98.00%
- Supply Ability: 50mg
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| | Aminooxy-PEG8-acid Basic information |
| | Aminooxy-PEG8-acid Chemical Properties |
| Boiling point | 575.8±50.0 °C(Predicted) | | density | 1.150±0.06 g/cm3(Predicted) | | pka | 4.28±0.10(Predicted) |
| | Aminooxy-PEG8-acid Usage And Synthesis |
| Uses | Aminooxy-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | Biological Activity | Aminooxy-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | IC 50 | PEGs | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | Aminooxy-PEG8-acid Preparation Products And Raw materials |
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