ChemicalBook > Product Catalog >Natural Products >Alkaloids >(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol

(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol

(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol Suppliers list
Company Name: Chengdu Greenpure Biopharma CO.,Ltd
Tel: 18283602253; +8618283602253
Email: jancyzheng@gcgreenpure.com
Products Intro: Product Name:Reticuline
CAS:485-19-8
Purity:98% Package:5mg
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:(S)-reticuline
CAS:485-19-8
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: Shanghai Zheyan Biotech Co., Ltd.
Tel: 18017610038
Email: zheyansh@163.com
Products Intro: Product Name:Reticuline
CAS:485-19-8
Purity:HPLC>=98% Package:5mg
Company Name: Chengdu Biopurify Phytochemicals Ltd.
Tel: +86-28-82633860; +8618080483897
Email: sales@biopurify.com
Products Intro: Product Name:(+)-Reticuline
CAS:485-19-8
Purity:0.98 Package:10mg;20mg;50mg;100mg
Company Name: Hubei Jusheng Technology Co.,Ltd.
Tel: 18871490254
Email: linda@hubeijusheng.com
Products Intro: Product Name:reticuline
CAS:485-19-8
Purity:99% Package:5KG;1KG Remarks:C19H23NO4
(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol Basic information
Product Name:(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol
Synonyms:(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol;(1S)-1-[(3-hydroxy-4-methoxy-phenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol;(S)-Reticuline;reticuline;[1S,(+)]-1,2,3,4-Tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol;[1S,(+)]-1,2,3,4-Tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinoline-7-ol;2-Methoxy-5-[[(1S)-2-methyl-6-methoxy-7-hydroxy-1,2,3,4-tetrahydroisoquinoline]-1-ylmethyl]phenol;Reticuline (>90% ee)
CAS:485-19-8
MF:C19H23NO4
MW:329.39
EINECS:207-611-3
Product Categories:Amines;Aromatics;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:485-19-8.mol
(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol Structure
(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol Chemical Properties
Melting point 125-126°C
Boiling point 648.96°C (rough estimate)
density 1.4371 (rough estimate)
refractive index 1.6800 (estimate)
storage temp. Sealed in dry,2-8°C
solubility Soluble in DMSO
pka9.95±0.10(Predicted)
form Solid
color Off-white to yellow
Optical Rotation+88.318 (c 0.21, ethanol)
InChIInChI=1S/C19H23NO4/c1-20-7-6-13-10-19(24-3)17(22)11-14(13)15(20)8-12-4-5-18(23-2)16(21)9-12/h4-5,9-11,15,21-22H,6-8H2,1-3H3/t15-/m0/s1
InChIKeyBHLYRWXGMIUIHG-HNNXBMFYSA-N
SMILES[C@H]1(CC2=CC=C(OC)C(O)=C2)C2=C(C=C(OC)C(O)=C2)CCN1C
Safety Information
MSDS Information
(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol Usage And Synthesis
Chemical PropertiesPale Yellow Solid
UsesReticulin can be used to improve production of morphinan alkaloids, as well as its anti-inflammatory properties. It can also be used to lead scaffolds as PDE5A inhibitors and antihypertensives.
UsesPrecursor of many aporphine and morphine-type alkaloids.
DefinitionChEBI: The (S)-enantiomer of reticuline.
in vivo

Reticuline (5, 10 and 20 mg/kg, i. v., randomly) injections produced an intense hypotension in normotensive rats. The hypotensive effect of Reticuline is probably due to a peripheral vasodilation in consequence of: 1) muscarinic stimulation and NOS activation in the vascular endothelium, 2) voltage-dependent Ca2+ channel blockade and/or 3) inhibition of Ca2+ release from norepinephrine-sensitive intracellular stores[2].

IC 50JAK2; STAT3; NF-κB; Human Endogenous Metabolite
(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol Preparation Products And Raw materials
Raw materialsIsoquinoline, 1,2,3,4-tetrahydro-6-methoxy-1-[[4-methoxy-3-(phenylmethoxy)phenyl]methyl]-2-methyl-7-(phenylmethoxy)-, (S)- (9CI)-->Cocculanorine (6CI,8CI)-->Isovanillin
Tag:(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol(485-19-8) Related Product Information
(+)-CORYDALINE BOLDINE DIMETHYL ETHER ISOCORYDINE HYDROCHLORIDE Narcotine (-)-BETA-HYDRASTINE ISOCORYDINE HYDROCHLORIDE (-)-STYLOPINE (+)-BULBOCAPNINE NOSCAPINE HYDROCHLORIDE L-TETRANDRINE BULBOCAPNINE HYDROCHLORIDE (-)-BICUCULLINE METHOCHLORIDE ESCHSCHOLTZINE HCL CALIFORNIDINE PERCHLORATE (+)-MENISPERINE IODIDE TIMTEC-BB SBB006457 NOSCAPINE HYDROCHLORIDE HYDRATE AKOS 208-02

  • HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
  • All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
    According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.
  • Copyright © 2023 ChemicalBook All rights reserved.