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(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol

(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol Suppliers list
Company Name: Chengdu Greenpure Biopharma CO.,Ltd
Tel: 18283602253; +8618283602253
Email: jancyzheng@gcgreenpure.com
Products Intro: Product Name:Reticuline
CAS:485-19-8
Purity:98% Package:5mg
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:(S)-reticuline
CAS:485-19-8
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: Shanghai Zheyan Biotech Co., Ltd.
Tel: 18017610038
Email: zheyansh@163.com
Products Intro: Product Name:Reticuline
CAS:485-19-8
Purity:HPLC>=98% Package:5mg
Company Name: Chengdu Biopurify Phytochemicals Ltd.
Tel: +86-28-82633860; +8618080483897
Email: sales@biopurify.com
Products Intro: Product Name:(+)-Reticuline
CAS:485-19-8
Purity:0.98 Package:10mg;20mg;50mg;100mg
Company Name: BOC Sciences
Tel: +1-631-485-4226
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Products Intro: Product Name:(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol
CAS:485-19-8
Purity:>97% Package:1mg Remarks:Reach out to us for more information about custom solutions.
(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol Basic information
Product Name:(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol
Synonyms:(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol;(1S)-1-[(3-hydroxy-4-methoxy-phenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol;(S)-Reticuline;reticuline;[1S,(+)]-1,2,3,4-Tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol;[1S,(+)]-1,2,3,4-Tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinoline-7-ol;2-Methoxy-5-[[(1S)-2-methyl-6-methoxy-7-hydroxy-1,2,3,4-tetrahydroisoquinoline]-1-ylmethyl]phenol;Reticuline (>90% ee)
CAS:485-19-8
MF:C19H23NO4
MW:329.39
EINECS:207-611-3
Product Categories:Amines;Aromatics;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:485-19-8.mol
(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol Structure
(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol Chemical Properties
Melting point 125-126°C
Boiling point 648.96°C (rough estimate)
density 1.4371 (rough estimate)
refractive index 1.6800 (estimate)
storage temp. Sealed in dry,2-8°C
solubility Soluble in DMSO
pka9.95±0.10(Predicted)
form Solid
color Off-white to yellow
Optical Rotation+88.318 (c 0.21, ethanol)
InChIInChI=1S/C19H23NO4/c1-20-7-6-13-10-19(24-3)17(22)11-14(13)15(20)8-12-4-5-18(23-2)16(21)9-12/h4-5,9-11,15,21-22H,6-8H2,1-3H3/t15-/m0/s1
InChIKeyBHLYRWXGMIUIHG-HNNXBMFYSA-N
SMILES[C@H]1(CC2=CC=C(OC)C(O)=C2)C2=C(C=C(OC)C(O)=C2)CCN1C
Safety Information
MSDS Information
(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol Usage And Synthesis
Chemical PropertiesPale Yellow Solid
UsesReticulin can be used to improve production of morphinan alkaloids, as well as its anti-inflammatory properties. It can also be used to lead scaffolds as PDE5A inhibitors and antihypertensives.
UsesPrecursor of many aporphine and morphine-type alkaloids.
DefinitionChEBI: The (S)-enantiomer of reticuline.
in vivo

Reticuline (5, 10 and 20 mg/kg, i. v., randomly) injections produced an intense hypotension in normotensive rats. The hypotensive effect of Reticuline is probably due to a peripheral vasodilation in consequence of: 1) muscarinic stimulation and NOS activation in the vascular endothelium, 2) voltage-dependent Ca2+ channel blockade and/or 3) inhibition of Ca2+ release from norepinephrine-sensitive intracellular stores[2].

IC 50JAK2; STAT3; NF-κB; Human Endogenous Metabolite
(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol Preparation Products And Raw materials
Raw materialsIsoquinoline, 1,2,3,4-tetrahydro-6-methoxy-1-[[4-methoxy-3-(phenylmethoxy)phenyl]methyl]-2-methyl-7-(phenylmethoxy)-, (S)- (9CI)-->Cocculanorine (6CI,8CI)-->Isovanillin
Tag:(S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol(485-19-8) Related Product Information
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