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TargetMol |
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| | mepacrine mesilate Basic information |
| Product Name: | mepacrine mesilate | | Synonyms: | mepacrine mesilate;quinacrine mesylate;1,4-Pentanediamine, N4-(6-chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-, dimethanesulfonate;Acridine, 6-chloro-9-((4-(diethylamino)-1-methylbutyl)amino)-2-methoxy-, dimethanesulfonate;Einecs 206-256-1;Mepacrine dimethanesulfonate salt;Mepacrine methanesulfonate;Musonal | | CAS: | 316-05-2 | | MF: | C24H34ClN3O4S | | MW: | 496.06 | | EINECS: | 206-256-1 | | Product Categories: | | | Mol File: | 316-05-2.mol |  |
| | mepacrine mesilate Chemical Properties |
| | mepacrine mesilate Usage And Synthesis |
| Uses | Quinacrine (Mepacrine) methanesulfonate is a potent, orally active antimalarial agent with antitumor effects in vitro and in vivo. Quinacrine dihydrochloride inhibits NF-κB and activates p53 signaling, inducing apoptosis in tumor cells[1][2]. | | References | [1] Xiaoyang Wu, et al. Quinacrine Inhibits Cell Growth and Induces Apoptosis in Human Gastric Cancer Cell Line SGC-7901. Curr Ther Res Clin Exp. 2012 Feb;73(1-2):52-64. DOI:10.1016/j.curtheres.2012.02.003
[2] Anna Eriksson, et al. Towards repositioning of quinacrine for treatment of acute myeloid leukemia - Promising synergies and in vivo effects. Leuk Res. 2017 Dec;63:41-46. DOI:10.1016/j.leukres.2017.10.012 |
| | mepacrine mesilate Preparation Products And Raw materials |
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