methyl (19alpha,20alpha)-16,17-didehydro-10,11-dimethoxy-19-methyloxayohimban-16-carboxylate

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Products Intro: Product Name:Isoreserpiline
CAS:572-67-8
Purity:95% Package:1mg;5mg;10mg
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Products Intro: Product Name:Isoreserpiline
CAS:572-67-8
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Products Intro: Product Name:methyl (19alpha,20alpha)-16,17-didehydro-10,11-dimethoxy-19-methyloxayohimban-16-carboxylate
CAS:572-67-8
Purity:98% Package:25KG
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Products Intro: Product Name:Isoreserpiline
CAS:572-67-8
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Products Intro: Product Name:Isoreserpiline
CAS:572-67-8
Purity:NA Package:1mg Remarks:SCAK-101544
methyl (19alpha,20alpha)-16,17-didehydro-10,11-dimethoxy-19-methyloxayohimban-16-carboxylate Basic information
Product Name:methyl (19alpha,20alpha)-16,17-didehydro-10,11-dimethoxy-19-methyloxayohimban-16-carboxylate
Synonyms:methyl (19alpha,20alpha)-16,17-didehydro-10,11-dimethoxy-19-methyloxayohimban-16-carboxylate;(20α)-16,17-Didehydro-10,11-dimethoxy-19α-methyl-18-oxayohimban-16-carboxylic acid methyl ester;3-Isoreserpiline;Einecs 209-342-7;Isoreserpilin;Oxayohimban-16-carboxylic acid, 16,17-didehydro-10,11-dimethoxy-19-methyl-, methyl ester, (19alpha,20alpha)-;Oxayohimban-16-carboxylic acid, 16,17-didehydro-10,11-dimethoxy-19-methyl-, methyl ester, (19α,20α)-
CAS:572-67-8
MF:C23H28N2O5
MW:412.47882
EINECS:209-342-7
Product Categories:
Mol File:572-67-8.mol
methyl (19alpha,20alpha)-16,17-didehydro-10,11-dimethoxy-19-methyloxayohimban-16-carboxylate Structure
methyl (19alpha,20alpha)-16,17-didehydro-10,11-dimethoxy-19-methyloxayohimban-16-carboxylate Chemical Properties
Melting point 211-212 °C (sublm)(Solv: ethyl ether (60-29-7))
Boiling point 569.9±50.0 °C(Predicted)
density 1.31±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO: soluble
form A solid
pka17.95±0.60(Predicted)
Safety Information
MSDS Information
methyl (19alpha,20alpha)-16,17-didehydro-10,11-dimethoxy-19-methyloxayohimban-16-carboxylate Usage And Synthesis
UsesIsoreserpiline is an orally active and BBB-penatrable indole alkaloids with antibacterial and antipsychotic activity. Isoreserpiline is even more effective when used in combination with antibiotics and inhibits the activity of bacterial efflux pumps. Isoreserpiline improves Amphetamine-induced hyperactivity in mice[1][2] .
References[1] Dwivedi GR, et al. Synergy Potential of Indole Alkaloids and Its Derivative against Drug-resistant Escherichia coli. Chem Biol Drug Des. 2015 Dec;86(6):1471-81. DOI:10.1111/cbdd.12613
[2] Gupta S, et al. Bioactivity guided isolation of antipsychotic constituents from the leaves of Rauwolfia tetraphylla L. Fitoterapia. 2012 Sep;83(6):1092-9. DOI:10.1016/j.fitote.2012.04.029
methyl (19alpha,20alpha)-16,17-didehydro-10,11-dimethoxy-19-methyloxayohimban-16-carboxylate Preparation Products And Raw materials
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