| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:CM764
CAS:1350296-29-5
Package:1removed
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CM 764 manufacturers
- CM764
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- $1520.00
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2026-05-11
- CAS:1350296-29-5
- Purity:
- Supply Ability: 10g
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| Product Name: | CM 764 | | Synonyms: | CM 764;2(3H)-Benzoxazolone, 6-acetyl-3-[4-[4-(2-amino-4-fluorophenyl)-1-piperazinyl]butyl]- | | CAS: | 1350296-29-5 | | MF: | C23H27FN4O3 | | MW: | 426.48 | | EINECS: | | | Product Categories: | | | Mol File: | 1350296-29-5.mol |  |
| | CM 764 Chemical Properties |
| Boiling point | 625.2±65.0 °C(Predicted) | | density | 1.274±0.06 g/cm3(Predicted) | | pka | 8.04±0.40(Predicted) |
| | CM 764 Usage And Synthesis |
| Description | CM764 is a potent and selective antagonist of sigma-2 receptors, a novel derivative of SN79. | | Uses | CM764 is an activator for sigma receptor with Ki of 86.6 and 3.5 nM for sigma-1 receptor and sigma-2 receptor. CM764 increases cytoplasmic calcium, NAD+/NADH, and ATP levels, and decreases the concentration of ROS[1]. | | IC 50 | Sigma 2 Receptor: 3.5 nM (Ki); Sigma 1 Receptor: 86.6 nM (Ki) | | References | [1] Nicholson H, et al., Sigma-2 Receptors Play a Role in Cellular Metabolism: Stimulation of Glycolytic Hallmarks by CM764 in Human SK-N-SH Neuroblastoma. J Pharmacol Exp Ther. 2016 Feb;356(2):232-43. DOI:10.1124/jpet.115.228387 |
| | CM 764 Preparation Products And Raw materials |
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