2’-beta-C-Ethynyl inosine manufacturers
|
| | 2’-beta-C-Ethynyl inosine Basic information |
| | 2’-beta-C-Ethynyl inosine Chemical Properties |
| Boiling point | 700.7±70.0 °C(Predicted) | | density | 1.76±0.1 g/cm3(Predicted) | | pka | 11.27±0.70(Predicted) |
| | 2’-beta-C-Ethynyl inosine Usage And Synthesis |
| Uses | 2’-Beta-C-Ethynyl inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 2’-Beta-C-Ethynyl inosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | | References | [1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
| | 2’-beta-C-Ethynyl inosine Preparation Products And Raw materials |
|