2,5-Dioxopyrrolidin-1-yl 8-azidooctanoate

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2,5-Dioxopyrrolidin-1-yl 8-azidooctanoate Basic information
Product Name:2,5-Dioxopyrrolidin-1-yl 8-azidooctanoate
Synonyms:2,5-Dioxopyrrolidin-1-yl 8-azidooctanoate;Octanoic acid, 8-azido-, 2,5-dioxo-1-pyrrolidinyl ester;2,5-Dioxopyrrolidin-1-yl 8-azidooctanoate , 8-Azido-octanoyl-OSu
CAS:2576471-56-0
MF:C12H18N4O4
MW:282.3
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Mol File:2576471-56-0.mol
2,5-Dioxopyrrolidin-1-yl 8-azidooctanoate Structure
2,5-Dioxopyrrolidin-1-yl 8-azidooctanoate Chemical Properties
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MSDS Information
2,5-Dioxopyrrolidin-1-yl 8-azidooctanoate Usage And Synthesis
Uses8-Azido-octanoyl-OSu is a click chemistry reagent containing an azide group. Used as a building block to introduce 8-azidooctanoic acid (CAS 217180-76-2) fragment. This fragment is used for further modifications using Click-chemistry (CuAAC), as a protected aminogroup or is used in physico-chemical investigations[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
References[1] Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14(8):779-789. DOI:10.1080/17460441.2019.1614910
2,5-Dioxopyrrolidin-1-yl 8-azidooctanoate Preparation Products And Raw materials
Tag:2,5-Dioxopyrrolidin-1-yl 8-azidooctanoate(2576471-56-0) Related Product Information
5-(2,5-dioxopyrrolidin-1-yl)oxy-5-oxopentanoic acid Dodecanedioic acid, 1,12-bis(2,5-dioxo-1-pyrrolidinyl) ester Decanedioic acid, 1-(2,5-dioxo-1-pyrrolidinyl) ester Nonadecanedioic acid, 1-(2,5-dioxo-1-pyrrolidinyl) ester Hexanedioic acid, 1-(2,5-dioxo-1-pyrrolidinyl) ester 13-((2,5-dioxopyrrolidin-1-yl)oxy)-13-oxotridecanoic acid