| Company Name: |
TargetMol
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| Tel: |
400-821-0310 15002144251 |
| Email: |
xuexiang.shao@tsbiochem.com |
| Products Intro: |
Product Name:Ac-Atovaquone
CAS:129700-44-3
Package:5mg/RMB 5230;1mg/RMB 1350;10mg/RMB 7320
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| | 1,4-Naphthalenedione, 2-(acetyloxy)-3-[trans-4-(4-chlorophenyl)cyclohexyl]-1,4-dihydro- Basic information |
| | 1,4-Naphthalenedione, 2-(acetyloxy)-3-[trans-4-(4-chlorophenyl)cyclohexyl]-1,4-dihydro- Chemical Properties |
| Melting point | 163.1 °C(Solv: ethanol (64-17-5)) | | Boiling point | 557.9±50.0 °C(Predicted) | | density | 1.31±0.1 g/cm3(Predicted) |
| | 1,4-Naphthalenedione, 2-(acetyloxy)-3-[trans-4-(4-chlorophenyl)cyclohexyl]-1,4-dihydro- Usage And Synthesis |
| Uses | Ac-Atovaquone is a potent cytochrome bc1 inhibitor and also is an ester-linked acetyl derivative of atovaquone (HY-13832). Ac-Atovaquone has the potential for the research of malaria[1][1][2]. | | References | [1] Siqueira-Neto JL, et al. Antimalarial drug discovery: progress and approaches. Nat Rev Drug Discov. 2023 Oct;22(10):807-826. doi: 10.1038/s41573-023-00772-9. Epub 2023 Aug 31. Erratum in: Nat Rev Drug Discov. 2024 Nov;23(11):880.
[2] El Gaaloul M, et al. Chemoprevention of malaria with long-acting oral and injectable drugs: an updated target product profile. Malar J. 2024 Oct 18;23(1):315. DOI:10.1186/s12936-024-05128-1 |
| | 1,4-Naphthalenedione, 2-(acetyloxy)-3-[trans-4-(4-chlorophenyl)cyclohexyl]-1,4-dihydro- Preparation Products And Raw materials |
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