Benzamide, N-[3-(1H-benzimidazol-2-yl)-1H-pyrazol-5-yl]-4-(4-methyl-1-piperazinyl)-

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Benzamide, N-[3-(1H-benzimidazol-2-yl)-1H-pyrazol-5-yl]-4-(4-methyl-1-piperazinyl)- manufacturers

  • FOXO1-IN-3
  • FOXO1-IN-3 pictures
  • 2026-05-11
  • CAS:2451093-95-9
  • Purity:
  • Supply Ability: 10g
Benzamide, N-[3-(1H-benzimidazol-2-yl)-1H-pyrazol-5-yl]-4-(4-methyl-1-piperazinyl)- Basic information
Product Name:Benzamide, N-[3-(1H-benzimidazol-2-yl)-1H-pyrazol-5-yl]-4-(4-methyl-1-piperazinyl)-
Synonyms:Benzamide, N-[3-(1H-benzimidazol-2-yl)-1H-pyrazol-5-yl]-4-(4-methyl-1-piperazinyl)-;N-(3-(1H-benzo[d]imidazol-2-yl)-1H-pyrazol-5-yl)-4-(4-methylpiperazin-1-yl)benzamide;FOXO1-IN-3
CAS:2451093-95-9
MF:C22H23N7O
MW:401.46
EINECS:
Product Categories:
Mol File:2451093-95-9.mol
Benzamide, N-[3-(1H-benzimidazol-2-yl)-1H-pyrazol-5-yl]-4-(4-methyl-1-piperazinyl)- Structure
Benzamide, N-[3-(1H-benzimidazol-2-yl)-1H-pyrazol-5-yl]-4-(4-methyl-1-piperazinyl)- Chemical Properties
density 1.364±0.06 g/cm3(Predicted)
pka10.68±0.10(Predicted)
form Solid
color Off-white to yellow
Safety Information
MSDS Information
Benzamide, N-[3-(1H-benzimidazol-2-yl)-1H-pyrazol-5-yl]-4-(4-methyl-1-piperazinyl)- Usage And Synthesis
UsesFOXO1-IN-3 is a highly-selective and orally active FOXO1 inhibitor. FOXO1-IN-3 reduces hepatic glucose production in mice. FOXO1-IN-3 improves insulin sensitivity and glucose control in db/db mice without causing weight gain[1].
References[1] Lee YK, et al. FOXO1 inhibition synergizes with FGF21 to normalize glucose control in diabetic mice. Mol Metab. 2021 Jul;49:101187. DOI:10.1016/j.molmet.2021.101187
Benzamide, N-[3-(1H-benzimidazol-2-yl)-1H-pyrazol-5-yl]-4-(4-methyl-1-piperazinyl)- Preparation Products And Raw materials
Tag:Benzamide, N-[3-(1H-benzimidazol-2-yl)-1H-pyrazol-5-yl]-4-(4-methyl-1-piperazinyl)-(2451093-95-9) Related Product Information
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