2H-1-Benzopyran, 3-(ethoxymethyl)-7-methoxy-2-(3,4,5-trimethoxyphenyl)-

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2H-1-Benzopyran, 3-(ethoxymethyl)-7-methoxy-2-(3,4,5-trimethoxyphenyl)- Basic information
Product Name:2H-1-Benzopyran, 3-(ethoxymethyl)-7-methoxy-2-(3,4,5-trimethoxyphenyl)-
Synonyms:2H-1-Benzopyran, 3-(ethoxymethyl)-7-methoxy-2-(3,4,5-trimethoxyphenyl)-;TNF-α-IN-14
CAS:364039-54-3
MF:C22H26O6
MW:386.44
EINECS:
Product Categories:
Mol File:364039-54-3.mol
2H-1-Benzopyran, 3-(ethoxymethyl)-7-methoxy-2-(3,4,5-trimethoxyphenyl)- Structure
2H-1-Benzopyran, 3-(ethoxymethyl)-7-methoxy-2-(3,4,5-trimethoxyphenyl)- Chemical Properties
Boiling point 496.9±45.0 °C(Predicted)
density 1.139±0.06 g/cm3(Predicted)
Safety Information
MSDS Information
2H-1-Benzopyran, 3-(ethoxymethyl)-7-methoxy-2-(3,4,5-trimethoxyphenyl)- Usage And Synthesis
UsesTNF-α-IN-14 is a potent and selective TNFα inhibitor with an IC50 value of 1.1 μM. TNF-α-IN-14 shows antiinflammatory properties (WO2001072735A2; compound 12)[1].
IC 50TNF-α: 1.1 μM (IC50)
References[1] Jie Fei Cheng, et al. Benzopyranes useful as tnf alpha inhibitors. WO2001072735A2.
2H-1-Benzopyran, 3-(ethoxymethyl)-7-methoxy-2-(3,4,5-trimethoxyphenyl)- Preparation Products And Raw materials
Tag:2H-1-Benzopyran, 3-(ethoxymethyl)-7-methoxy-2-(3,4,5-trimethoxyphenyl)-(364039-54-3) Related Product Information
Ethanone, 1-[7-methoxy-2-(3,4,5-trimethoxyphenyl)-2H-1-benzopyran-3-yl]- 2H-1-Benzopyran-3-carboxamide, 7-methoxy-2-(3,4,5-trimethoxyphenyl)- 2H-1-Benzopyran-3-carboxaldehyde, 7-methoxy-2-(3,4,5-trimethoxyphenyl)- 2H-1-Benzopyran-3-carbonitrile, 7-methoxy-2-(3,4,5-trimethoxyphenyl)- CD40 Protein, HUMAN (HEK293, FC) TRAIL R1/TNFRSF10A protein, HUMAN (BIOTINYLATED, HEK293, HIS-AVI)