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Shanghai Yifei Biotechnology Co. , Ltd.
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021-65675885 18964387627 |
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customer_service@efebio.com |
| Products Intro: |
Product Name:Adenosine-5'-O-(3-thiotriphosphate) (sodium salt)
CAS:88453-52-5
Purity:95% Package:2.6mg
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| Company Name: |
TargetMol Chemicals Inc.
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15002134094 |
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marketing@targetmol.cn |
| Products Intro: |
Product Name:ATP-γ-S tetrasodium
CAS:88453-52-5
Package:2600μg/RMB 2780
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| Company Name: |
Cayman Chemical Company
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800-364-9897 |
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sales@caymanchem.com |
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Product Name:Adenosine-5'-O-(3-thiotriphosphate) (sodium salt)
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Enzo Biochem Inc
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Enzo Biochem Inc. 13797054060 |
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Enzoname@qq.com |
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Product Name:ATP-γ-S
CAS:88453-52-5
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| Company Name: |
Biorbyt Ltd.
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+44 (0)1223 859 353 |
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info@biorbyt.com |
| Products Intro: |
Product Name:Adenosine-5'-O-(3-thiotriphosphate) sodium
CAS:88453-52-5
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| | Adenosine 5'-(trihydrogen diphosphate), monoanhydride with phosphorothioic acid, tetrasodium salt (9CI) Basic information |
| | Adenosine 5'-(trihydrogen diphosphate), monoanhydride with phosphorothioic acid, tetrasodium salt (9CI) Chemical Properties |
| solubility | Water: Soluble |
| | Adenosine 5'-(trihydrogen diphosphate), monoanhydride with phosphorothioic acid, tetrasodium salt (9CI) Usage And Synthesis |
| Uses | ATP-γ-S (tetrasodium) is a P2Y11 receptor agonist, an antioxidant and a neuroprotective agent. ATP-γ-S (tetrasodium) can be used as a substrate for the nucleotide hydrolysis and RNA unwinding activities of eukaryotic translation initiation factor eIF4A. ATP-γ-S (tetrasodium) is active in ATP hydrolysis[1][2][3][4][5]. | | in vivo | ATPγS (tetralithium salt, 50 μM final, intravenous) demonstrates preserved lung parenchymal architecture[3].
ATPγS results in a dose-dependent effect on EBA extravasation in LPS-treated mice[3].
| | References | [1] Matthew L Peck, et al. Adenosine 5'-O-(3-thio)triphosphate (ATPgammaS) is a substrate for the nucleotide hydrolysis and RNA unwinding activities of eukaryotic translation initiation factor eIF4A. RNA. 2003 Oct;9(10):1180-7. DOI:10.1261/rna.2103703
[2] Z Y Wang, et al. Mg2+ and ATP or adenosine 5'-[gamma-thio]-triphosphate (ATP gamma S) enhances intrinsic fluorescence and induces aggregation which increases the activity of spinach Rubisco activase. Biochim Biophys Acta. 1993 Sep 3;1202(1):47-55. DOI:10.1016/0167-4838(93)90061-u
[3] Irina A Kolosova, et al. Protective effect of purinergic agonist ATPgammaS against acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2008 Feb;294(2):L319-24. DOI:10.1152/ajplung.00283.2007
[4] Ortal Danino, et al. ATP-γ-S-(α,β-CH2) protects against oxidative stress and amyloid beta toxicity in neuronal culture. Biochem Biophys Res Commun. 2015 May 1;460(2):446-50. DOI:10.1016/j.bbrc.2015.03.053
[5] J W Lee, et al. Inhibition of recA protein promoted ATP hydrolysis. 1. ATP gamma S and ADP are antagonistic inhibitors. Biochemistry. 1990 Aug 21;29(33):7666-76. DOI:10.1021/bi00485a016
[6] A D QI. An arginine/glutamine difference at the juxtaposition of transmembrane domain 6 and the third extracellular loop contributes to the markedly different nucleotide selectivities of human and canine P2Y11 receptors.[J]. Molecular Pharmacology, 2001, 60 6 1: 1375-1382. DOI: 10.1124/mol.60.6.1375
[7] VICTORIA B AYALA-PEÑA. Infection of Rat Osteoblasts with Junin Virus Promotes the Expression of Bone Morphogenetic Protein 6, an Osteogenic Differentiation Inducer.[J]. Intervirology, 2019, 62 1: 1-8. DOI: 10.1159/000499466
[8] SEBASTIAN HAUKE. ATP is an essential autocrine factor for pancreatic β-cell signaling and insulin secretion.[J]. Physiological Reports, 2022, 10 1: e15159. DOI: 10.14814/phy2.15159 |
| | Adenosine 5'-(trihydrogen diphosphate), monoanhydride with phosphorothioic acid, tetrasodium salt (9CI) Preparation Products And Raw materials |
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