adenosine 5'-(tetrahydrogen triphosphate), 2'-deoxy-3'-O-(azidomethyl)-

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adenosine 5'-(tetrahydrogen triphosphate), 2'-deoxy-3'-O-(azidomethyl)- Basic information
Product Name:adenosine 5'-(tetrahydrogen triphosphate), 2'-deoxy-3'-O-(azidomethyl)-
Synonyms:adenosine 5'-(tetrahydrogen triphosphate), 2'-deoxy-3'-O-(azidomethyl)-;3′-O-Azidomethyl-dATP 100mM Sodium Solution;3'-azidomethyl-2'-Deoxyadenosine-5'-Triphosphate;3'-azidomethyl-dATP;3’-N3-dATP;[[(2R,3S,5R)-5-(6-aminopurin-9-yl)-3-(azidomethoxy)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate;3'-O-Azidomethyl-2'-deoxyadenosine 5'-triphosphate
CAS:1048021-78-8
MF:C11H17N8O12P3
MW:546.22
EINECS:
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Mol File:1048021-78-8.mol
adenosine 5'-(tetrahydrogen triphosphate), 2'-deoxy-3'-O-(azidomethyl)- Structure
adenosine 5'-(tetrahydrogen triphosphate), 2'-deoxy-3'-O-(azidomethyl)- Chemical Properties
pka0.796±0.50(predicted)
Safety Information
MSDS Information
adenosine 5'-(tetrahydrogen triphosphate), 2'-deoxy-3'-O-(azidomethyl)- Usage And Synthesis
Uses3′-O-N3-dATP (3′-O-Azidomethyl dATP) is a modified nucleotide, which is utilized for DNA polymerase. 3′-O-N3-dATP acts as reversible terminator with enhanced raman scattering (SERS) at 2125 cm-1, which determines the DNA sequences continuously[1].
References[1] Palla M, et al., DNA sequencing by synthesis using 3'-O-azidomethyl nucleotide reversible terminators and surface-enhanced Raman spectroscopic detection. RSC Adv. 2014 Jan 1;4(90):49342-49346. DOI:10.1039/C4RA08398A
adenosine 5'-(tetrahydrogen triphosphate), 2'-deoxy-3'-O-(azidomethyl)- Preparation Products And Raw materials
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