| Company Name: |
Changsha Luxing Bio-Chem Technology Co., Ltd.
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| Tel: |
0731-88827538 15574813303 |
| Email: |
luxingbc@126.com |
| Products Intro: |
Product Name:1-(2-methoxyethyl)-4-pyrazole carbaldehyde
CAS:304693-70-7
Purity:97% HPLC Package:100g 1kg 5kg 10kg
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| | 1H-Pyrazole-4-carboxaldehyde, 1-(2-methoxyethyl)- (9CI) Basic information |
| Product Name: | 1H-Pyrazole-4-carboxaldehyde, 1-(2-methoxyethyl)- (9CI) | | Synonyms: | 1H-Pyrazole-4-carboxaldehyde, 1-(2-methoxyethyl)- (9CI);1-(2-methoxyethyl)-4-pyrazolecarboxaldehyde;1-(2-methoxyethyl)pyrazole-4-carbaldehyde;1-(2-methoxyethyl)-1H-pyrazole-4-carboxaldehyde;1-(2-Methoxyethyl)-1H-pyrazol-4-carbaldehyde;1-(2-methoxyethyl)-4-pyrazole carbaldehyde | | CAS: | 304693-70-7 | | MF: | C7H10N2O2 | | MW: | 154.17 | | EINECS: | | | Product Categories: | ALDEHYDE | | Mol File: | 304693-70-7.mol |  |
| | 1H-Pyrazole-4-carboxaldehyde, 1-(2-methoxyethyl)- (9CI) Chemical Properties |
| Boiling point | 269.8±20.0 °C(Predicted) | | density | 1.14±0.1 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | pka | -0.05±0.10(Predicted) | | Appearance | Colorless to light yellow Liquid |
| | 1H-Pyrazole-4-carboxaldehyde, 1-(2-methoxyethyl)- (9CI) Usage And Synthesis |
| Synthesis | GENERAL STEPS: 1H-pyrazole-4-carbaldehyde (500 mg, 5.20 mmol) was dissolved in N,N-dimethylformamide (DMF, 20 mL), and 2-bromoethyl methyl ether (713 mg, 5.2 mmol) and cesium carbonate (Cs2CO3, 3.40 g, 10.4 mmol) were added in sequence. The reaction mixture was stirred at 60 °C overnight. After completion of the reaction, water (20 mL) was added to the mixture and extracted with ethyl acetate (EtOAc, 50 mL x 3). The organic phases were combined, washed with saturated brine, dried over anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure to afford the target product 1-(2-methoxyethyl)-1H-pyrazole-4-carbaldehyde (520 mg, 65% yield). | | References | [1] Patent: WO2018/50684, 2018, A1. Location in patent: Page/Page column 68
[2] Patent: WO2018/50686, 2018, A1. Location in patent: Page/Page column 72; 73 |
| | 1H-Pyrazole-4-carboxaldehyde, 1-(2-methoxyethyl)- (9CI) Preparation Products And Raw materials |
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