ZYJ 34v manufacturers
- ZYJ-34v
-
- $2500.00
-
2026-04-20
- CAS:1450662-32-4
- Purity:
- Supply Ability: 10g
|
| | ZYJ 34v Basic information |
| | ZYJ 34v Chemical Properties |
| density | 1.230±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 8.795±0.20(predicted) |
| | ZYJ 34v Usage And Synthesis |
| Description | ZYJ-34v is an oral active histone deacetylase inhibitor with potent antitumor activity. | | Uses | ZYJ-34v is an orally active histone deacetylase inhibitor. ZYJ-34v has antitumor activity[1]. | | in vivo | ZYJ-34v (90 mg/kg, orally, for 22 days) shows antitumor activity in MDA-MB-231 xenograft tumor model[1].
| Animal Model: | a mouse MDA-MB-231 xenograft model[1] | | Dosage: | 90 mg/kg | | Administration: | p.o. | | Result: | Decreased the final tumor volume. |
| | References | [1] Zhang Y, et al. Design and synthesis of a tetrahydroisoquinoline-based hydroxamate derivative (ZYJ-34v), an oral active histone deacetylase inhibitor with potent antitumor activity. Chem Biol Drug Des. 2013 Aug;82(2):125-30. DOI:10.1111/cbdd.12144 |
| | ZYJ 34v Preparation Products And Raw materials |
|