- 6-Hydroxyindole
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- $9.85 / 1KG
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2026-03-20
- CAS:2380-86-1
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10 m
- 6-Hydroxyindole
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- $29.00 / 100mg
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2026-03-13
- CAS:2380-86-1
- Min. Order:
- Purity: 99.14%
- Supply Ability: 10g
- 6-Hydroxyindole
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- $0.00 / 100g
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2025-09-22
- CAS:2380-86-1
- Min. Order: 100g
- Purity: 98%
- Supply Ability: 10kgs
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| | 6-Hydroxyindole Basic information |
| | 6-Hydroxyindole Chemical Properties |
| Melting point | 125-128 °C | | Boiling point | 343.2±15.0 °C(Predicted) | | density | 1.327±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,2-8°C | | solubility | Chloroform (Slightly, Heated), Methanol (Slightly) | | pka | 10.07±0.40(Predicted) | | form | Shiny Crystalline Powder | | color | White to off-white | | Cosmetics Ingredients Functions | HAIR DYEING | | Cosmetic Ingredient Review (CIR) | 6-Hydroxyindole (2380-86-1) | | InChI | InChI=1S/C8H7NO/c10-7-2-1-6-3-4-9-8(6)5-7/h1-5,9-10H | | InChIKey | XAWPKHNOFIWWNZ-UHFFFAOYSA-N | | SMILES | N1C2=C(C=CC(O)=C2)C=C1 | | CAS DataBase Reference | 2380-86-1(CAS DataBase Reference) |
| Hazard Codes | Xi,N,Xn | | Risk Statements | 36/37/38-51/53-43-41-22 | | Safety Statements | 37/39-26-61-24-2 | | RIDADR | UN 3077 | | WGK Germany | 3 | | Hazard Note | Irritant | | HazardClass | 9 | | HazardClass | IRRITANT, KEEP COLD | | PackingGroup | Ⅲ | | HS Code | 29339900 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral
Aquatic Chronic 2
Eye Dam. 1
Skin Sens. 1 |
| Provider | Language |
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ACROS
| English |
| | 6-Hydroxyindole Usage And Synthesis |
| Chemical Properties | White to off-white shiny crystalline powder | | Uses | - Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
- Reactant for asymmetrical synthesis of notoamide J as a potential biosynthetic precursor of prenylated indole alkaloids
- Reactant for preparation of (quinolinyloxymethyl)isoxazolecarboxylate esters antituberculosis agents
- Reactant for preparation of indolyl(propanolamine) derivatives as HIV inhibitors
- Reactant for preparation of indoleoxyacetic acid derivatives as peroxisome proliferator-activated receptor agonists
- Reactant for preparation of 1-aroylindole 3-aroylindoles combretastatin A-4 analogs as antitumor agents and tubulin polymerization inhibitors
| | Synthesis Reference(s) | Journal of Medicinal Chemistry, 35, p. 2419, 1992 DOI: 10.1021/jm00091a010 | | Synthesis | Regioselective chloroacetylation of 1-pivaloylindole followed by Baeyer-Villiger oxidation offers introduction of an oxygen function into the 6-position of the indole ring. Deacylation of 6-chloroacetyl-1-pivaloylindole gives 6-hydroxyindole. The overall yield of 6-hydroxyindole from indole is 54%.
[1] K. TERANISHI; T. G; S I NAKATSUKA. ChemInform Abstract: Facile Synthesis of 6-Hydroxyindole (VII) and 6-Methoxyindole (IX) via Regioselective Friedel-Crafts Acylation and Baeyer-Villiger Oxidation.[J]. ChemInform, 1995, 26 9. DOI:10.1002/chin.199509120. |
| | 6-Hydroxyindole Preparation Products And Raw materials |
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