L-JNKI-1
L-JNKI-1 性质
| 储存条件 | -20°C |
|---|---|
| 溶解度 | water: 2 mg/mL |
| 形态 | 固体 |
| 颜色 | 白色至米白色 |
| 水溶解性 | water: 2mg/mL |
L-JNKI-1 是一种针对 JNK 的细胞渗透性多肽抑制剂。
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JNK
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L-JNKI-1 has been shown to effectively inhibit JNK activity in in vivo studies. It is shown that Ang II induces a dose-dependent pressor response, which was significantly attenuated by JNK inhibition. It is also found that 10 μM L-JNKI-1 decreases phosphorylated c-Jun by 98% and phosphorylated Elk-1 by 100%. L-JNKI-1 is able to across the blood-brain barrier and penetrate neurons of adult mice and P5 rats within 1 h after an intraperitoneal injection.
安全信息
| WGK Germany | WGK 1 |
|---|---|
| 存储类别 | 11 - 可燃固体 |