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| | 1-BROMO-2,3,5,6-TETRAFLUOROBENZENE Basic information |
| Product Name: | 1-BROMO-2,3,5,6-TETRAFLUOROBENZENE | | Synonyms: | BROMO-2,3,5,6-TETRAFLUOROBENZENE;1-BROMO-2,3,5,6-TETRAFLUOROBENZENE;1-Bromo-2,3,5,6-tetrafluorbenzene;Benzene, 3-bromo-1,2,4,5-tetrafluoro-;1-Bromo-2,3,5,6-tetrafluorobenzene 99%;1-Bromo-2,3,5,6-tetrafluorobenzene99%;1-Bromo-2,3,5,6-tetrafluorobenzene,2,3,5,6-Tetrafluorobromobenzene;2,3,5,6-Tetrafluorobromobenzene98% | | CAS: | 1559-88-2 | | MF: | C6HBrF4 | | MW: | 228.97 | | EINECS: | 216-327-9 | | Product Categories: | Benzene series;Aryl;Halogenated Hydrocarbons;C6 | | Mol File: | 1559-88-2.mol |  |
| | 1-BROMO-2,3,5,6-TETRAFLUOROBENZENE Chemical Properties |
| Boiling point | 143-143.5 °C(lit.) | | density | 1.883 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.469(lit.) | | Fp | 129 °F | | storage temp. | Sealed in dry,Room Temperature | | form | clear liquid | | Specific Gravity | 1.883 | | color | Colorless to Almost colorless | | Water Solubility | Not miscible or difficult to mix in water. | | CAS DataBase Reference | 1559-88-2(CAS DataBase Reference) |
| | 1-BROMO-2,3,5,6-TETRAFLUOROBENZENE Usage And Synthesis |
| Chemical Properties | clear colorless liquid | | Uses | 1-Bromo-2,3,5,6-tetrafluorobenzene is used to produce 1,2,4,5-tetrafluoro-3-hept-1-ynyl-benzene. It is also used as a pharmaceutical intermediate. | | Synthesis | Potassium salt of 2,3,5,6-tetrafluorobenzoic acid (100 g) was added to dimethylformamide (250 ml) and stirred in a glass reactor equipped with a mechanical stirrer, a dropping funnel, a separator, a Liebig condenser, an adapter and a receiving flask, the reaction mixture was heated to 140 C and bromotrichloromethane (85 g) was added in such a way as to maintain a 140-143 C temperature while distilling out the resulting product. This process was continued until the end of the outgassing. The distillate was mixed with the cube and washed with two volumes of 15% perchloric acid. The lower (organic) layer was separated, hydrodistilled, then dried and distilled with CaCl2. 1-Bromo-2,3,5,6-tetrafluorobenzene (89 g) was obtained with a boiling point of 144C and a yield of 91%. |
| | 1-BROMO-2,3,5,6-TETRAFLUOROBENZENE Preparation Products And Raw materials |
| Raw materials | 2,3,5,6-TETRAFLUOROTHIOPHENOL-->Bromopentafluorobenzene-->4-BROMOTETRAFLUOROPHENYLHYDRAZINE-->1,4-DIBROMOTETRAFLUOROBENZENE-->1,2,4,5-Tetrafluorobenzene-->2,3,5,6-Tetrafluorobenzoic acid-->Sodium benzenolate | | Preparation Products | 1,1'-Biphenyl, 2,2',3,3',4,4',5,6,6'-nonafluoro--->Bromobenzene |
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