Benzamide, N-(1,2-dihydro-4,7-dimethyl-2-oxo-6-quinolinyl)-5-[(dimethylamino)sulfonyl]-2-(4-morpholinyl)-

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Company Name: Shandong Dayou Pharmaceutical Research and Development Co., Ltd.  
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Company Name: TargetMol Chemicals Inc.  
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Company Name: TargetMol Chemicals Inc.  
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Benzamide, N-(1,2-dihydro-4,7-dimethyl-2-oxo-6-quinolinyl)-5-[(dimethylamino)sulfonyl]-2-(4-morpholinyl)- manufacturers
Benzamide, N-(1,2-dihydro-4,7-dimethyl-2-oxo-6-quinolinyl)-5-[(dimethylamino)sulfonyl]-2-(4-morpholinyl)- Basic information
Product Name:Benzamide, N-(1,2-dihydro-4,7-dimethyl-2-oxo-6-quinolinyl)-5-[(dimethylamino)sulfonyl]-2-(4-morpholinyl)-
Synonyms:Benzamide, N-(1,2-dihydro-4,7-dimethyl-2-oxo-6-quinolinyl)-5-[(dimethylamino)sulfonyl]-2-(4-morpholinyl)-;Bromodomain inhibitor-9
CAS:1870849-34-5
MF:C24H28N4O5S
MW:484.57
EINECS:
Product Categories:
Mol File:1870849-34-5.mol
Benzamide, N-(1,2-dihydro-4,7-dimethyl-2-oxo-6-quinolinyl)-5-[(dimethylamino)sulfonyl]-2-(4-morpholinyl)- Structure
Benzamide, N-(1,2-dihydro-4,7-dimethyl-2-oxo-6-quinolinyl)-5-[(dimethylamino)sulfonyl]-2-(4-morpholinyl)- Chemical Properties
density 1.330±0.06 g/cm3(Predicted)
pka11.09±0.70(Predicted)
Safety Information
MSDS Information
Benzamide, N-(1,2-dihydro-4,7-dimethyl-2-oxo-6-quinolinyl)-5-[(dimethylamino)sulfonyl]-2-(4-morpholinyl)- Usage And Synthesis
UsesBromodomain inhibitor-9 is a Bromodomains inhibitor that selectively inhibits BRD4-1 (Kd: 12 nM). Bromodomain inhibitor-9 can be used in the research of diseases or conditions associated with systemic or tissue inflammation, lipid metabolism, fibrosis or chronic autoimmune diseases[1].
IC 50BRD4-1: 12 nM (Kd); BRD4-2: 5600 nM (Kd)
References[1] Gerner Seitzberg, et al. Heterocyclic compounds as inhibitors of bromodomains and their preparation. Patent WO2016016316.
Benzamide, N-(1,2-dihydro-4,7-dimethyl-2-oxo-6-quinolinyl)-5-[(dimethylamino)sulfonyl]-2-(4-morpholinyl)- Preparation Products And Raw materials
Tag:Benzamide, N-(1,2-dihydro-4,7-dimethyl-2-oxo-6-quinolinyl)-5-[(dimethylamino)sulfonyl]-2-(4-morpholinyl)-(1870849-34-5) Related Product Information
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