AIDS058893 manufacturers
- GL-331
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- $1520.00
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2026-05-11
- CAS:127882-73-9
- Purity:
- Supply Ability: 10g
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| | AIDS058893 Basic information |
| Product Name: | AIDS058893 | | Synonyms: | AIDS058893;(5R)-5,5aα,8aβ,9-Tetrahydro-9α-[4-nitrophenylamino]-5β-(4-hydroxy-3,5-dimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(8H)-one;(5R)-5,8,8aβ,9-Tetrahydro-5β-(4-hydroxy-3,5-dimethoxyphenyl)-9α-[(4-nitrophenyl)amino]furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxole-6(5aαH)-one;(5R)-5β-(3,5-Dimethoxy-4-hydroxyphenyl)-7α-(hydroxymethyl)-8α-(4-nitrophenylamino)-5,6,7,8-tetrahydronaphtho[2,3-d]-1,3-dioxole-6β-carboxylic acid 6,7-lactone;(5R)-5β-(4-Hydroxy-3,5-dimethoxyphenyl)-9α-(4-nitrophenylamino)-5,5aα,6,8,8aβ,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d]-1,3-dioxole-6-one;W-68;Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-9-[(4-nitrophenyl)amino]-, (5R,5aR,8aS,9S)-;(5R,5aR,8aS,9S)-5-(4-hydroxy-3,5-dimethoxyphenyl)-9-((4-nitrophenyl)amino)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one | | CAS: | 127882-73-9 | | MF: | C27H24N2O9 | | MW: | 520.49 | | EINECS: | | | Product Categories: | | | Mol File: | 127882-73-9.mol |  |
| | AIDS058893 Chemical Properties |
| Melting point | 206-207 °C(Solv: ethyl acetate (141-78-6)) | | Boiling point | 751.5±60.0 °C(Predicted) | | density | 1.459±0.06 g/cm3(Predicted) | | pka | 9.94±0.40(Predicted) |
| | AIDS058893 Usage And Synthesis |
| Uses | GL-331 is a potent anti-cancer agent. GL-331 has demonstrated more efficacious anti-cancer activity in both the in vitro and in vivo lymphoma systems[1]. | | References | [1] You Y. Podophyllotoxin derivatives: current synthetic approaches for new anticancer agents. Curr Pharm Des. 2005;11(13):1695-717. DOI:10.2174/1381612053764724 [2] Huang TS, et al. A novel podophyllotoxin-derived compound GL331 is more potent than its congener VP-16 in killing refractory cancer cells. Pharm Res. 1999 Jul;16(7):997-1002. DOI:10.1023/a:1018971313256 |
| | AIDS058893 Preparation Products And Raw materials |
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