Benzoic acid, 4-[[4,6-bis[[4-(aminosulfonyl)phenyl]amino]-1,3,5-triazin-2-yl]amino]- manufacturers
- AChE-IN-20
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- $1520.00
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2026-05-11
- CAS:2428389-65-3
- Purity:
- Supply Ability: 10g
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| | Benzoic acid, 4-[[4,6-bis[[4-(aminosulfonyl)phenyl]amino]-1,3,5-triazin-2-yl]amino]- Basic information |
| | Benzoic acid, 4-[[4,6-bis[[4-(aminosulfonyl)phenyl]amino]-1,3,5-triazin-2-yl]amino]- Chemical Properties |
| Boiling point | 896.5±75.0 °C(Predicted) | | density | 1.648±0.06 g/cm3(Predicted) | | pka | 4.45±0.10(Predicted) |
| | Benzoic acid, 4-[[4,6-bis[[4-(aminosulfonyl)phenyl]amino]-1,3,5-triazin-2-yl]amino]- Usage And Synthesis |
| Uses | AChE-IN-20 (compound M26) is a potent AChE inhibitor with IC50 value of 397.32 nM and with Ki value of 335.76 nM. AChE-IN-20 shows inhibition potency against hCA I , hCA II and α-GLY with IC50 values of 84.14, 69.24 and 52.08 nM and with Ki values of 97.86, 76.23 and 57.93 nM, respectively[1]. | | IC 50 | AChE: 397.32 nM (IC50); AChE: 335.76 nM (Ki) | | References | [1] Lolak N, et al. Synthesis, characterization, inhibition effects, and molecular docking studies as acetylcholinesterase, α-glycosidase, and carbonic anhydrase inhibitors of novel benzenesulfonamides incorporating 1,3,5-triazine structural motifs. Bioorg Chem. 2020 Jul;100:103897. DOI:10.1016/j.bioorg.2020.103897 |
| | Benzoic acid, 4-[[4,6-bis[[4-(aminosulfonyl)phenyl]amino]-1,3,5-triazin-2-yl]amino]- Preparation Products And Raw materials |
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