Acetamide, N-(4-ethylphenyl)-2-[[3-(2-furanyl)-1H-1,2,4-triazol-5-yl]thio]-

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Acetamide, N-(4-ethylphenyl)-2-[[3-(2-furanyl)-1H-1,2,4-triazol-5-yl]thio]- Basic information

Product Name:	Acetamide, N-(4-ethylphenyl)-2-[[3-(2-furanyl)-1H-1,2,4-triazol-5-yl]thio]-
Synonyms:	Acetamide, N-(4-ethylphenyl)-2-[[3-(2-furanyl)-1H-1,2,4-triazol-5-yl]thio]-;Neuraminidase-IN-6
CAS:	2738526-22-0
MF:	C16H16N4O2S
MW:	328.39
EINECS:
Product Categories:
Mol File:	2738526-22-0.mol

Acetamide, N-(4-ethylphenyl)-2-[[3-(2-furanyl)-1H-1,2,4-triazol-5-yl]thio]- Chemical Properties

density	1.36±0.1 g/cm3(Predicted)
pka	8.30±0.40(Predicted)

Safety Information

MSDS Information

Acetamide, N-(4-ethylphenyl)-2-[[3-(2-furanyl)-1H-1,2,4-triazol-5-yl]thio]- Usage And Synthesis

Uses	Neuraminidase-IN-6 (Compound 5c) is a potent inhibitor of neuraminidase with an IC50 of 0.11 μM. Neuraminidase-IN-6 is a 1,3,4-triazole-3-acetamide derivative. Neuraminidase (NA) is an ideal target for the development of anti-influenza agents[1].
References	[1] Shi L, et al. Design, synthesis and biological evaluation of 1,3,4-triazole-3-acetamide derivatives as potent neuraminidase inhibitors. Bioorg Med Chem Lett. 2022;61:128590. DOI:10.1016/j.bmcl.2022.128590

Acetamide, N-(4-ethylphenyl)-2-[[3-(2-furanyl)-1H-1,2,4-triazol-5-yl]thio]- Preparation Products And Raw materials

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