1-Piperidinepropanamide, 4-[4-[[5-chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-2-methyl-5-(1-methylethoxy)phenyl]-N-[2-[2-[(1-oxo-2-propen-1-yl)amino]ethoxy]ethyl]- manufacturers
- Con B-1
-
- $1520.00
-
2026-05-11
- CAS:2415537-51-6
- Purity:
- Supply Ability: 10g
|
| | 1-Piperidinepropanamide, 4-[4-[[5-chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-2-methyl-5-(1-methylethoxy)phenyl]-N-[2-[2-[(1-oxo-2-propen-1-yl)amino]ethoxy]ethyl]- Basic information |
| | 1-Piperidinepropanamide, 4-[4-[[5-chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-2-methyl-5-(1-methylethoxy)phenyl]-N-[2-[2-[(1-oxo-2-propen-1-yl)amino]ethoxy]ethyl]- Chemical Properties |
| density | 1.234±0.06 g/cm3(Predicted) | | pka | 14.32±0.46(Predicted) |
| | 1-Piperidinepropanamide, 4-[4-[[5-chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-2-methyl-5-(1-methylethoxy)phenyl]-N-[2-[2-[(1-oxo-2-propen-1-yl)amino]ethoxy]ethyl]- Usage And Synthesis |
| Uses | ConB-1 is a potent and selective ALK inhibitor with low toxicity to normal cells[1]. | | References | [1] Yan G, et al. Targeting Cysteine Located Outside the Active Site: An Effective Strategy for Covalent ALKi Design. J Med Chem. 2021 Feb 11;64(3):1558-1569. DOI:10.1021/acs.jmedchem.0c01707 |
| | 1-Piperidinepropanamide, 4-[4-[[5-chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-2-methyl-5-(1-methylethoxy)phenyl]-N-[2-[2-[(1-oxo-2-propen-1-yl)amino]ethoxy]ethyl]- Preparation Products And Raw materials |
|