7H-Pyrrolo[2,3-d]pyridazin-7-one, 4-amino-3-[2-(2-cyclopropyl-5-benzoxazolyl)ethynyl]-1,6-dihydro-1-[(3S)-1-(1-oxo-2-propen-1-yl)-3-pyrrolidinyl]-

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7H-Pyrrolo[2,3-d]pyridazin-7-one, 4-amino-3-[2-(2-cyclopropyl-5-benzoxazolyl)ethynyl]-1,6-dihydro-1-[(3S)-1-(1-oxo-2-propen-1-yl)-3-pyrrolidinyl]- Basic information
Product Name:7H-Pyrrolo[2,3-d]pyridazin-7-one, 4-amino-3-[2-(2-cyclopropyl-5-benzoxazolyl)ethynyl]-1,6-dihydro-1-[(3S)-1-(1-oxo-2-propen-1-yl)-3-pyrrolidinyl]-
Synonyms:7H-Pyrrolo[2,3-d]pyridazin-7-one, 4-amino-3-[2-(2-cyclopropyl-5-benzoxazolyl)ethynyl]-1,6-dihydro-1-[(3S)-1-(1-oxo-2-propen-1-yl)-3-pyrrolidinyl]-;FGFR-IN-5
CAS:2762750-70-7
MF:C25H22N6O3
MW:454.48
EINECS:
Product Categories:
Mol File:2762750-70-7.mol
7H-Pyrrolo[2,3-d]pyridazin-7-one, 4-amino-3-[2-(2-cyclopropyl-5-benzoxazolyl)ethynyl]-1,6-dihydro-1-[(3S)-1-(1-oxo-2-propen-1-yl)-3-pyrrolidinyl]- Structure
7H-Pyrrolo[2,3-d]pyridazin-7-one, 4-amino-3-[2-(2-cyclopropyl-5-benzoxazolyl)ethynyl]-1,6-dihydro-1-[(3S)-1-(1-oxo-2-propen-1-yl)-3-pyrrolidinyl]- Chemical Properties
density 1.53±0.1 g/cm3(Predicted)
pka12.28±0.40(Predicted)
Safety Information
MSDS Information
7H-Pyrrolo[2,3-d]pyridazin-7-one, 4-amino-3-[2-(2-cyclopropyl-5-benzoxazolyl)ethynyl]-1,6-dihydro-1-[(3S)-1-(1-oxo-2-propen-1-yl)-3-pyrrolidinyl]- Usage And Synthesis
UsesFGFR-IN-5 is a potent inhibitor of FGFR. Fibroblast growth factor receptor (FGFR) is a tyrosine kinase receptor that binds to fibroblast growth factor ligands. FGFR-IN-5 has the potential for the research of cancer diseases (extracted from patent WO2022042612A1, compound 3)[1]. FGFR-IN-5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
References[1] Haibin Deng, et al. Dihydropyrrolo[2,3-d]pyridazin-7-one derivative, preparation method therefor, and application thereof. Patent WO2022042612A1.
7H-Pyrrolo[2,3-d]pyridazin-7-one, 4-amino-3-[2-(2-cyclopropyl-5-benzoxazolyl)ethynyl]-1,6-dihydro-1-[(3S)-1-(1-oxo-2-propen-1-yl)-3-pyrrolidinyl]- Preparation Products And Raw materials
Tag:7H-Pyrrolo[2,3-d]pyridazin-7-one, 4-amino-3-[2-(2-cyclopropyl-5-benzoxazolyl)ethynyl]-1,6-dihydro-1-[(3S)-1-(1-oxo-2-propen-1-yl)-3-pyrrolidinyl]-(2762750-70-7) Related Product Information
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