1-Pyrrolidinecarboxylic acid, 2-[(3-pyridinylamino)carbonyl]-, 2-(4-nitrobenzoyl)hydrazide, (2R)-

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1-Pyrrolidinecarboxylic acid, 2-[(3-pyridinylamino)carbonyl]-, 2-(4-nitrobenzoyl)hydrazide, (2R)- Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

1-Pyrrolidinecarboxylic acid, 2-[(3-pyridinylamino)carbonyl]-, 2-(4-nitrobenzoyl)hydrazide, (2R)- manufacturers

  • CDK4/6-IN-8
  • CDK4/6-IN-8 pictures
  • $2500.00
  • 2026-07-27
  • CAS:2649120-22-7
  • Purity:
  • Supply Ability: 10g
1-Pyrrolidinecarboxylic acid, 2-[(3-pyridinylamino)carbonyl]-, 2-(4-nitrobenzoyl)hydrazide, (2R)- Basic information
Product Name:1-Pyrrolidinecarboxylic acid, 2-[(3-pyridinylamino)carbonyl]-, 2-(4-nitrobenzoyl)hydrazide, (2R)-
Synonyms:1-Pyrrolidinecarboxylic acid, 2-[(3-pyridinylamino)carbonyl]-, 2-(4-nitrobenzoyl)hydrazide, (2R)-;CDK4/6-IN-8
CAS:2649120-22-7
MF:C18H18N6O5
MW:398.37
EINECS:
Product Categories:
Mol File:2649120-22-7.mol
1-Pyrrolidinecarboxylic acid, 2-[(3-pyridinylamino)carbonyl]-, 2-(4-nitrobenzoyl)hydrazide, (2R)- Structure
1-Pyrrolidinecarboxylic acid, 2-[(3-pyridinylamino)carbonyl]-, 2-(4-nitrobenzoyl)hydrazide, (2R)- Chemical Properties
density 1.466±0.06 g/cm3(Predicted)
pka9.56±0.40(Predicted)
Safety Information
MSDS Information
1-Pyrrolidinecarboxylic acid, 2-[(3-pyridinylamino)carbonyl]-, 2-(4-nitrobenzoyl)hydrazide, (2R)- Usage And Synthesis
UsesCDK4/6-IN-8 (Compound 7p) is a selective CDK4 and CDK6 inhibitor with IC50 values of 5.01 nM and 3.97 nM, respectively[1].
IC 50CDK6: 3.97 nM (IC50); CDK4: 5.01 nM (IC50)
References[1] Liang JW, et al. Synthesis and identification of a novel skeleton of N-(pyridin-3-yl) proline as a selective CDK4/6 inhibitor with anti-breast cancer activities. Bioorg Chem. 2022 Feb;119:105547. DOI:10.1016/j.bioorg.2021.105547
1-Pyrrolidinecarboxylic acid, 2-[(3-pyridinylamino)carbonyl]-, 2-(4-nitrobenzoyl)hydrazide, (2R)- Preparation Products And Raw materials
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