| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:CDK4/6-IN-8
CAS:2649120-22-7
Package:100mg/RMB 17500;25mg/RMB 10600;50mg/RMB 13800
|
1-Pyrrolidinecarboxylic acid, 2-[(3-pyridinylamino)carbonyl]-, 2-(4-nitrobenzoyl)hydrazide, (2R)- manufacturers
- CDK4/6-IN-8
-
- $2500.00 / 100mg
-
2026-01-04
- CAS:2649120-22-7
- Min. Order:
- Purity:
- Supply Ability: 10g
|
| | 1-Pyrrolidinecarboxylic acid, 2-[(3-pyridinylamino)carbonyl]-, 2-(4-nitrobenzoyl)hydrazide, (2R)- Basic information |
| | 1-Pyrrolidinecarboxylic acid, 2-[(3-pyridinylamino)carbonyl]-, 2-(4-nitrobenzoyl)hydrazide, (2R)- Chemical Properties |
| density | 1.466±0.06 g/cm3(Predicted) | | pka | 9.56±0.40(Predicted) |
| | 1-Pyrrolidinecarboxylic acid, 2-[(3-pyridinylamino)carbonyl]-, 2-(4-nitrobenzoyl)hydrazide, (2R)- Usage And Synthesis |
| Uses | CDK4/6-IN-8 (Compound 7p) is a selective CDK4 and CDK6 inhibitor with IC50 values of 5.01 nM and 3.97 nM, respectively[1]. | | IC 50 | CDK6: 3.97 nM (IC50); CDK4: 5.01 nM (IC50) | | References | [1] Liang JW, et al. Synthesis and identification of a novel skeleton of N-(pyridin-3-yl) proline as a selective CDK4/6 inhibitor with anti-breast cancer activities. Bioorg Chem. 2022 Feb;119:105547. DOI:10.1016/j.bioorg.2021.105547 |
| | 1-Pyrrolidinecarboxylic acid, 2-[(3-pyridinylamino)carbonyl]-, 2-(4-nitrobenzoyl)hydrazide, (2R)- Preparation Products And Raw materials |
|