Spiro[cyclopropane-1,10'-[10H]pyrido[3',4':4,5]pyrrolo[2,3-f]isoquinolin]-7'(6'H)-one, 2'-(3,4-dihydro-4-methyl-2H-1,4-benzoxazin-7-yl)-5',8',9',11'-tetrahydro-

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Spiro[cyclopropane-1,10'-[10H]pyrido[3',4':4,5]pyrrolo[2,3-f]isoquinolin]-7'(6'H)-one, 2'-(3,4-dihydro-4-methyl-2H-1,4-benzoxazin-7-yl)-5',8',9',11'-tetrahydro- Suppliers list
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Spiro[cyclopropane-1,10'-[10H]pyrido[3',4':4,5]pyrrolo[2,3-f]isoquinolin]-7'(6'H)-one, 2'-(3,4-dihydro-4-methyl-2H-1,4-benzoxazin-7-yl)-5',8',9',11'-tetrahydro- Basic information
Product Name:Spiro[cyclopropane-1,10'-[10H]pyrido[3',4':4,5]pyrrolo[2,3-f]isoquinolin]-7'(6'H)-one, 2'-(3,4-dihydro-4-methyl-2H-1,4-benzoxazin-7-yl)-5',8',9',11'-tetrahydro-
Synonyms:Spiro[cyclopropane-1,10'-[10H]pyrido[3',4':4,5]pyrrolo[2,3-f]isoquinolin]-7'(6'H)-one, 2'-(3,4-dihydro-4-methyl-2H-1,4-benzoxazin-7-yl)-5',8',9',11'-tetrahydro-;MK2-IN-4
CAS:1105658-32-9
MF:C25H24N4O2
MW:412.48
EINECS:
Product Categories:
Mol File:1105658-32-9.mol
Spiro[cyclopropane-1,10'-[10H]pyrido[3',4':4,5]pyrrolo[2,3-f]isoquinolin]-7'(6'H)-one, 2'-(3,4-dihydro-4-methyl-2H-1,4-benzoxazin-7-yl)-5',8',9',11'-tetrahydro- Structure
Spiro[cyclopropane-1,10'-[10H]pyrido[3',4':4,5]pyrrolo[2,3-f]isoquinolin]-7'(6'H)-one, 2'-(3,4-dihydro-4-methyl-2H-1,4-benzoxazin-7-yl)-5',8',9',11'-tetrahydro- Chemical Properties
Boiling point 784.6±60.0 °C(Predicted)
density 1.45±0.1 g/cm3(Predicted)
pka14.45±0.20(Predicted)
Safety Information
MSDS Information
Spiro[cyclopropane-1,10'-[10H]pyrido[3',4':4,5]pyrrolo[2,3-f]isoquinolin]-7'(6'H)-one, 2'-(3,4-dihydro-4-methyl-2H-1,4-benzoxazin-7-yl)-5',8',9',11'-tetrahydro- Usage And Synthesis
UsesMK2-IN-4 is a MAPKAPK2 (MK2) inhibitor with an IC50 value of 45 nM. MK2-IN-4 can be used in the research of cancer, inflammation, immunology[1].
References[1] Schlapbach, et al. Heterocyclic compounds useful as MK2 inhibitors and their preparation, pharmaceutical compositions and use in the treatment of diseases. Patent WO2009010488.
Spiro[cyclopropane-1,10'-[10H]pyrido[3',4':4,5]pyrrolo[2,3-f]isoquinolin]-7'(6'H)-one, 2'-(3,4-dihydro-4-methyl-2H-1,4-benzoxazin-7-yl)-5',8',9',11'-tetrahydro- Preparation Products And Raw materials
Tag:Spiro[cyclopropane-1,10'-[10H]pyrido[3',4':4,5]pyrrolo[2,3-f]isoquinolin]-7'(6'H)-one, 2'-(3,4-dihydro-4-methyl-2H-1,4-benzoxazin-7-yl)-5',8',9',11'-tetrahydro-(1105658-32-9) Related Product Information
C-PEPTIDE (HUMAN) 2-Cyano-N-(2-hydroxy-1,1-dimethylethyl)-3-[3-(3,4,5-trimethoxyphenyl)-1H-indazol-5-yl]-2-propenamide 8H-[1,4]Diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one, 3-[[2-chloro-5-(ethoxymethyl)-4-pyrimidinyl]oxy]-9,10,11,12-tetrahydro-10-methyl-, (10R)- Spiro[azetidine-3,10'-[10H]pyrido[3',4':4,5]pyrrolo[2,3-f]isoquinolin]-7'(6'H)-one, 2'-(2-fluorophenyl)-5',8',9',11'-tetrahydro-1-methyl- L-Alanine, L-tyrosyl-L-alanyl-L-arginyl-L-alanyl-L-alanyl-L-alanyl-L-arginyl-L-glutaminyl-L-alanyl-L-arginyl-L-alanyl-L-lysyl-L-alanyl-L-leucyl-L-alanyl-L-arginyl-L-glutaminyl-L-leucylglycyl-L-valyl-L-alanyl- [1(2H),4'-Bipyridin]-2-one, 3-chloro-4-[(3,5-difluoro-2-pyridinyl)methoxy]-2'-[2-(1-hydroxy-1-methylethyl)-4-pyrimidinyl]-5',6-dimethyl-, (2'S)-