1H-Pyrazole-1-carboxamide, 5-[5-bromo-1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-1H-indol-3-yl]-4,5-dihydro-3-[4-(trifluoromethyl)phenyl]-, (5S)-

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1H-Pyrazole-1-carboxamide, 5-[5-bromo-1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-1H-indol-3-yl]-4,5-dihydro-3-[4-(trifluoromethyl)phenyl]-, (5S)- Suppliers list
Company Name: TargetMol Chemicals Inc.  
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Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
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Company Name: TargetMol Chemicals Inc.  
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Company Name: Shanghai Amole Biotechnology Co., Ltd.  
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1H-Pyrazole-1-carboxamide, 5-[5-bromo-1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-1H-indol-3-yl]-4,5-dihydro-3-[4-(trifluoromethyl)phenyl]-, (5S)- manufacturers

  • JAK2/STAT3-IN-1
  • JAK2/STAT3-IN-1 pictures
  • $293.00
  • 2026-08-19
  • CAS:2485758-50-5
  • Purity: 97.35%
  • Supply Ability: 10g
1H-Pyrazole-1-carboxamide, 5-[5-bromo-1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-1H-indol-3-yl]-4,5-dihydro-3-[4-(trifluoromethyl)phenyl]-, (5S)- Basic information
Product Name:1H-Pyrazole-1-carboxamide, 5-[5-bromo-1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-1H-indol-3-yl]-4,5-dihydro-3-[4-(trifluoromethyl)phenyl]-, (5S)-
Synonyms:1H-Pyrazole-1-carboxamide, 5-[5-bromo-1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-1H-indol-3-yl]-4,5-dihydro-3-[4-(trifluoromethyl)phenyl]-, (5S)-;JAK2/STAT3-IN-1
CAS:2485758-50-5
MF:C34H35BrF3N5O2
MW:682.57
EINECS:
Product Categories:
Mol File:2485758-50-5.mol
1H-Pyrazole-1-carboxamide, 5-[5-bromo-1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-1H-indol-3-yl]-4,5-dihydro-3-[4-(trifluoromethyl)phenyl]-, (5S)- Structure
1H-Pyrazole-1-carboxamide, 5-[5-bromo-1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-1H-indol-3-yl]-4,5-dihydro-3-[4-(trifluoromethyl)phenyl]-, (5S)- Chemical Properties
Boiling point 776.2±70.0 °C(Predicted)
density 1.44±0.1 g/cm3(Predicted)
pka15+-.0.60(Predicted)
Safety Information
MSDS Information
1H-Pyrazole-1-carboxamide, 5-[5-bromo-1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-1H-indol-3-yl]-4,5-dihydro-3-[4-(trifluoromethyl)phenyl]-, (5S)- Usage And Synthesis
UsesJAK2/STAT3-IN-1 (compound (S)-10a) is a potent GP130 inhibitor with an IC50 of 3.04 μM. JAK2/STAT3-IN-1 shows anti-tumor activity[1].
References[1] Song D, et al. Discovery of bazedoxifene analogues targeting glycoprotein 130. Eur J Med Chem. 2020 Aug 1;199:112375. DOI:10.1016/j.ejmech.2020.112375
1H-Pyrazole-1-carboxamide, 5-[5-bromo-1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-1H-indol-3-yl]-4,5-dihydro-3-[4-(trifluoromethyl)phenyl]-, (5S)- Preparation Products And Raw materials
Tag:1H-Pyrazole-1-carboxamide, 5-[5-bromo-1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-1H-indol-3-yl]-4,5-dihydro-3-[4-(trifluoromethyl)phenyl]-, (5S)-(2485758-50-5) Related Product Information
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