| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:HF50731 CAS:2484771-19-7 Package:100mg/RMB 17500;25mg/RMB 10600;50mg/RMB 13800
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HF50731 manufacturers
- HF50731
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- $2500.00 / 100mg
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2026-04-13
- CAS:2484771-19-7
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | HF50731 Basic information |
| | HF50731 Chemical Properties |
| Boiling point | 568.8±50.0 °C(Predicted) | | density | 1.01±0.1 g/cm3(Predicted) | | pka | 11.21±0.20(Predicted) |
| | HF50731 Usage And Synthesis |
| Uses | HF50731 (compound 21) is a potent CXCR4 antagonist. HF50731 shows strong CXCR4 binding affinity, with IC50 of 19.8 nM. HF50731 effectively inhibits calcium mobilization, cell migration, and HIV-1 infection via CXCR4 coreceptor, with IC50 values of 119.2 nM, 621.4 nM and 1.5 μM[1]. | | IC 50 | CXCR4: 19.8 nM (IC50); HIV-1: 1.5 μM (IC50) | | References | [1] Fang X, Meng Q, Zhang H, Liang B, Zhu S, Wang J, Zhang C, Huang LS, Zhang X, Schooley RT, An J, Xu Y, Huang Z. Design, synthesis, and biological characterization of a new class of symmetrical polyamine-based small molecule CXCR4 antagonists. Eur J Med Chem. 2020 Aug 15;200:112410. DOI:10.1016/j.ejmech.2020.112410 |
| | HF50731 Preparation Products And Raw materials |
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